alpha 2 Macroglobulin Protein

Produktnummer ABIN934820

Produktdetails

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Protein-Typ: Native

Spezies: Human

Quelle: Human

Produktmerkmale: Purified native Human alpha 2 Macroglobulin protein
Protein Source: Human plasma

Reinheit: > 95 % pure

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from 30 mM Na0 O4, pH 7.0, with glycine as a stabilizer.

Vorsichtsmaßnahmen: Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 °C.

Referenzen

Rahman, Jeng, Singh, Coughlin, Essani, McFadden: "Interaction of human TNF and beta2-microglobulin with Tanapox virus-encoded TNF inhibitor, TPV-2L." in: Virology, Vol. 386, Issue 2, pp. 462-8, (2009) (PubMed).

Antigendetails

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Andere Bezeichnung: alpha 2 Macroglobulin (A2M Produkte)

Synonyme: A2MD Protein, CPAMD5 Protein, FWP007 Protein, S863-7 Protein, A2MAC1 Protein, A2m1 Protein, A2maa Protein, Mam Protein, A2mp Protein, A2M Protein, LOC733429 Protein, endod Protein, cpamd5 Protein, fwp007 Protein, s863-7 Protein, a2mb Protein, endodermin Protein, Alpha-2-M Protein, alpha-2-macroglobulin Protein, pregnancy-zone protein L homeolog Protein, alpha-2-macroglobulin S homeolog Protein, pregnancy zone protein Protein, alpha-2-macroglobulin-like Protein, A2M Protein, A2m Protein, LOC477699 Protein, pzp.L Protein, AZL_c00450 Protein, LOC100349077 Protein, a2m Protein, LOC100061656 Protein, LOC100090399 Protein, a2m.S Protein, LOC100469973 Protein, LOC100595735 Protein, PZP Protein, LOC100353095 Protein, LOC101122940 Protein, LOC101801552 Protein, LOC100911545 Protein

Hintergrund: A major serum protein found at concentrations of 240 mg per 100 ml in men and 290 mg per 100 ml in women. Multifunctional, it promotes growth of mammalian cells in culture, stimulates the regeneration of lymphocytes in irradiated mice, possesses a transport function for zinc and is a proteinase inhibitor that controls the clotting and fibrinolytic system. Clinically levels are increased in liver cirrhosis, nephrotic syndrome, diabetes, and severe burn cases. .
Description: Human plasma.
Alternative Names: A2M protein, alpha Macroglobulin 2, S863 7 protein, alpha Macroglobulin-2 protein, alpha 2 Macroglobulin, alpha 2 M protein, alpha Macroglobulin-2, DKFZp779B086 protein, alpha 2M protein, alpha Macroglobulin 2 protein, CPAMD5 protein, FWP007 protein

Molekulargewicht: 725 kDa

Pathways: Lipid Metabolism