Prothrombin Protein

Produktnummer ABIN934835

Produktdetails

Target: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Protein-Typ: Native

Biologische Aktivität: Active

Spezies: Human

Quelle: Human

Produktmerkmale: Purified native Human Prothrombin protein
Bioactivity: 9.7 units/mg protein - One unit of activity is equivalent to the Prothrombin activity in one milliliter of human normal plasma.
Protein Source: Human serum/plasma

Reinheit: > 98 % pure

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as a liquid with 50 % Glycerol/H2 O (vol/vol).

Vorsichtsmaßnahmen: Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 °C.

Antigendetails

Target: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Andere Bezeichnung: Prothrombin (F2 Produkte)

Synonyme: PT Protein, RPRGL2 Protein, THPH1 Protein, Cf-2 Protein, Cf2 Protein, FII Protein, thrombin Protein, zgc:66319 Protein, wu:fb57c10 Protein, wu:fd42e09 Protein, wu:fd59d01 Protein, prothrombin Protein, F2 Protein, coagulation factor II, thrombin Protein, coagulation factor II Protein, coagulation factor II (thrombin) Protein, F2 Protein, f2 Protein

Hintergrund: Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to gamma-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes.
Description: Human serum/plasma.

Molekulargewicht: 72 kDa

Pathways: Komplementsystem, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling