Recoverin is a heterogeneously acylated calcium-binding and intracellular signal transduction protein in the photoreceptor cells of retina. Recoverin contains four EF-hands, of which two bind Ca. Ca-induced extrusion of the acyl group from a hydrophobic cleft in the protein drives the translocation of recoverin from solution to the disc membrane. Recently, recoverin is a detectable serologic protein that is expressed in patients with cancer-associated retinopathy, a paraneoplastic syndrome. Recombinant human recoverin was overexpressed in E. coli and purified by using conventional chromatography techniques. Alternative Names: Protein CAR protein, Cancer associated retinopathy protein protein, Cancer associated retinopathy protein antibody protein, RCVRN protein, , Recoverin protein, CAR protein protein, RCV1 protein, Cancer-associated retinopathy protein protein, Recoverin protein