ENO2/NSE Protein (AA 1-434)

Produktnummer ABIN934970

Produktdetails

Target: ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 1-434

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Sequenz: MSIEKIWARE ILDSRGNPTV EVDLYTAKGL FRAAVPSGAS TGIYEALELR DGDKQRYLGK GVLKAVDHIN STIAPALISS GLSVVEQEKL DNLMLELDGT ENKSKFGANA ILGVSLAVCK AGAAERELPL YRHIAQLAGN SDLILPVPAF NVINGGSHAG NKLAMQEFMI LPVGAESFRD AMRLGAEVYH TLKGVIKDKY GKDATNVGDE GGFAPNILEN SEALELVKEA IDKAGYTEKI VIGMDVAASE FYRDGKYDLD FKSPTDPSRY ITGDQLGALY QDFVRDYPVV SIEDPFDQDD WAAWSKFTAN VGIQIVGDDL TVTNPKRIER AVEEKACNCL LLKVNQIGSV TEAIQACKLA QENGWGVMVS HRSGETEDTF IADLVVGLCT GQIKTGAPCR SERLAKYNQL MRIEEELGDE ARFAGHNFRN PSVL

Produktmerkmale: Purified recombinant Human NSE protein
Expression System: E.coli
Bioactivity: Specific activity: > 8 units/mL. One unit will convert 1.0 m of 2-phosphoglycerate to phospho(enol)pyruvate per minute at pH 7.5 at 25C
Molecular weight on SDS-PAGE will appear higher.

Reinheit: > 95 % pure

Endotoxin-Niveau: < 1.0 EU per µg of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: NSE protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris, pH 7.5, containing 0.1 M KCl, and 5 mM MgSO4.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Antigendetails

Target: ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))

Andere Bezeichnung: NSE (ENO2 Produkte)

Synonyme: ENO2 Protein, DKFZp459B1817 Protein, NSE Protein, AI837106 Protein, D6Ertd375e Protein, Eno-2 Protein, RNEN3 Protein, eno3 Protein, wu:fc09h05 Protein, zgc:92418 Protein, enolase 2 Protein, enolase 2 (gamma, neuronal) Protein, enolase 2, gamma neuronal Protein, enolase 2, gamma, neuronal Protein, ENO2 Protein, Eno2 Protein, eno2 Protein

Hintergrund: Neuron-specific enolase (NSE) is a glycolytic isoenzyme which is located in central and peripheral neurons and neuroendocrine cells. This enzyme is released into the CSF when neural tissue is injured. Neoplasms derived from neural or neuroendocrine tissue may release NSE into the blood. NSE is a useful substance that has been detected in patients with certain tumors, namely: neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and melanoma. Recombinant NSE was expressed in E. coli and purified by conventional chromatography techniques.
Alternative Names: ENO2 protein, Enolase 2 gamma neuronal protein, neuronal) protein, Neuron specific enolase protein, Neuron specific gamma enolase protein, NSE protein, Gamma enolase protein, 2 phospho D glycerate hydrolyase protein, ENOG protein, Neuron-Specific Enolase protein, Eno 2 protein, Neurone specific enolase., Enolase 2 (gamma protein, Neural enolase protein, Enolase2 protein

Molekulargewicht: 47 kDa ( 434 AA)