NME1 Protein (AA 1-152)

Produktnummer ABIN935048

Produktdetails

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-152

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Sequenz: MANCERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVGLKF MQASEDLLKE HYVDLKDRPF FAGLVKYMHS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS DSVESAEKEI GLWFHPEELV DYTSCAQNWI YE

Produktmerkmale: Purified recombinant Human NME1 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Reinheit: > 95 % pure

Endotoxin-Niveau: < 1.0 EU per µg of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: NME1 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, containing 0 mM DTT, and 10 % glycerol.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Antigendetails

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Andere Bezeichnung: NME1 (NME1 Produkte)

Synonyme: AWD Protein, GAAD Protein, NB Protein, NBS Protein, NDKA Protein, NDPK-A Protein, NDPKA Protein, NM23 Protein, NM23-H1 Protein, AL024257 Protein, NM23-M1 Protein, NM23A Protein, NDPK-Z1 Protein, NM23-B Protein, NM23-Z1 Protein, ndpkz1 Protein, nm23b Protein, nme1 Protein, nme2 Protein, nme2b1 Protein, NME1 Protein, NME1-NME2 Protein, NM23-C1 Protein, ndpk-b Protein, ndpkb Protein, nm23-h2 Protein, nm23ndk Protein, puf Protein, NBR-A Protein, NBR-B Protein, NME1-1 Protein, nm23ndk-a Protein, NDK I Protein, NDPK I Protein, T30A10.80 Protein, T30A10_80 Protein, NDP kinase I Protein, NME/NM23 nucleoside diphosphate kinase 1 Protein, NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 Protein, non-metastatic cells 1, protein (NM23A) expressed in Protein, NME/NM23 nucleoside diphosphate kinase 2 S homeolog Protein, NME/NM23 nucleoside diphosphate kinase 2 L homeolog Protein, nucleoside diphosphate kinase Protein, nucleoside diphosphate kinase 1 Protein, NME1 Protein, Nme1 Protein, nme2b.1 Protein, nme2.S Protein, nme2.L Protein, LOC547870 Protein, NDPK1 Protein, LOC107790563 Protein

Hintergrund: Non-metastatic cells 1 (NME1), also known as NM23-H1, originally identified as a candidate metastasis suppressor gene. NME1 is expressed in different tumor types where their levels have been alternatively associated with reduced or increased metastatic potential. Reductions in NME1 expression have been significantly associated with aggressive behavior in melanoma, breast, colon, and gastric carcinomas. On the contrary, high levels of NME1 gene expression are noted in the advanced stage of thyroid carcinomas. Recombinant human NME1 was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: NM23-H1 protein, NDP Kinase A protein, NME-1 protein, NM23H1B protein, NM23 long variant protein, Nonmetastatic protein 23 protein, protein expressed in protein, Granzyme A activated DNase protein, GZMA activated DNase protein, AWD protein, Nucleoside diphosphate kinase A protein, NDK A protein, NME-1, Nonmetastatic cells 1 protein, Non-metastatic cells 1 AWD protein, GAAD protein, included protein, Tumor metastatic process-associated protein., NDP kinase A protein, included protein, drosophila protein, included protein, NB protein, Nonmetastatic protein 23 protein, NME1-NME2 spliced read-through transcript protein, NME 1 protein, NM23 protein, NDPK-A protein, Metastasis inhibition factor nm23 protein, NBS protein, NM23-M1 protein, protein (NM23A) expressed in protein, NM23 protein, homolog of protein, homolog 1 protein, NME 1, NDPKA protein, NME1, Nucleoside diphosphate kinase A protein, NME1 protein, Non-metastatic cells 1 protein

Molekulargewicht: 17.1 kDa (152 AA)

Pathways: Apoptose, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process