ATF3 Protein (AA 1-181)
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- Target Alle ATF3 Proteine anzeigen
- ATF3 (Activating Transcription Factor 3 (ATF3))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-181
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S
- Produktmerkmale
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Purified recombinant ATF3 protein
Expression System: E.coli - Reinheit
- > 90 % pure
- Top Product
- Discover our top product ATF3 Protein
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- Applikationshinweise
- ATF3 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Supplied as a liquid in 20 mM Tris-HCl, pH 8.0, containing 2 M Urea and 20 % glycerol.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- RT/-20 °C
- Informationen zur Lagerung
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- Target
- ATF3 (Activating Transcription Factor 3 (ATF3))
- Andere Bezeichnung
- ATF3 (ATF3 Produkte)
- Hintergrund
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ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter.
Alternative Names: ATF 3, ATF-3 protein, ATF 3 protein, ATF3, ATF-3, Cyclic AMP dependent transcription factor ATF3 protein, ATF3deltaZip3 protein, ATF3deltaZip2 protein, cAMP dependent transcription factor ATF3 protein, ATF3deltaZip2c protein, Cyclic AMP-dependent transcription factor ATF-3 protein - Molekulargewicht
- 20.6kDa (181 AA)
- Pathways
- Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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