FLIP Protein (AA 1-480)

Produktnummer ABIN935116

Produktdetails

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-480

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Sequenz: MSAEVIHQVE EALDTDEKEM LLFLCRDVAI DVVPPNVRDL LDILRERGKL SVGDLAELLY RVRRFDLLKR ILKMDRKAVE THLLRNPHLV SDYRVLMAEI GEDLDKSDVS SLIFLMKDYM GRGKISKEKS FLDLVVELEK LNLVAPDQLD LLEKCLKNIH RIDLKTKIQK YKQSVQGAGT SYRNVLQAAI QKSLKDPSNN FRLHNGRSKE QRLKEQLGAQ QEPVKKSIQE SEAFLPQSIP EERYKMKSKP LGICLIIDCI GNETELLRDT FTSLGYEVQK FLHLSMHGIS QILGQFACMP EHRDYDSFVC VLVSRGGSQS VYGVDQTHSG LPLHHIRRMF MGDSCPYLAG KPKMFFIQNY VVSEGQLENS SLLEVDGPAM KNVEFKAQKR GLCTVHREAD FFWSLCTADM SLLEQSHSSP SLYLQCLSQK LRQERKRPLL DLHIELNGYM YDWNSRVSAK EKYYVWLQHT LRKKLILSYT

Produktmerkmale: Recombinant human CFLAR protein
Expression System: E.coli

Reinheit: > 85 % pure

Anwendungsinformationen

Applikationshinweise: CFLAR protein has been used in SDS PAGE, and may be suitable for use in other assays

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. 20 mM Tris-HCl buffer (pH8.0) containing 10 % glycerol.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Can be stored at 4 °C short term (1-2 weeks). For long term storage, aliquot and store at -20 °C or -70 °C.

Antigendetails

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Andere Bezeichnung: CFLAR (CFLAR Produkte)

Synonyme: Clarp1 Protein, cflar Protein, CFLAR Protein, FLIP Protein, CASH Protein, CASP8AP1 Protein, CLARP Protein, Casper Protein, FLAME Protein, FLAME-1 Protein, FLAME1 Protein, I-FLICE Protein, MRIT Protein, c-FLIP Protein, c-FLIPL Protein, c-FLIPR Protein, c-FLIPS Protein, 2310024N18Rik Protein, A430105C05Rik Protein, Cash Protein, ENSMUSG00000072980 Protein, Flip Protein, Gm9845 Protein, c-Flip Protein, CASP8 and FADD-like apoptosis regulator a Protein, CASP8 and FADD like apoptosis regulator Protein, CASP8 and FADD like apoptosis regulator S homeolog Protein, CASP8 and FADD-like apoptosis regulator Protein, cflara Protein, CFLAR Protein, cflar Protein, cflar.S Protein, Cflar Protein

Hintergrund: CFLAR, also known as FLIP, is involved in the regulation of apoptosis. It has been designated by independent groups as Casper, I-FLICE, CLARP, FLAME-1 and MRIT. Although its exact role is still being elucidated, it appears to be an important factor in the regulation of apoptosis downstream of all known death receptors. Recombinant human CFLAR protein was expressed in E.coli and denatured using detergent during a conventional chromatography purification process.
Alternative Names: c-FLIP protein, USURPIN protein, I-FLICE protein, FLIP protein, CLARP protein, MRIT protein, FLAME protein, Casper protein, FLAME1 protein, FLAME-1 protein, CASP8 and FADD-like apoptosis regulator protein, CASH protein

Molekulargewicht: 55.3 kDa (480 AA)

Pathways: Apoptose, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development