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Betacellulin Protein (BTC)

BTC Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN935244
  • Target Alle Betacellulin (BTC) Proteine anzeigen
    Betacellulin (BTC)
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 12
    • 4
    • 4
    • 2
    • 2
    Human
    Quelle
    • 13
    • 4
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Sequenz
    DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY
    Produktmerkmale
    Purified recombinant Human Betacellulin protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse Balb/3T3 cells is ? 0.05 ng/mL, corresponding to a specific activity of ? 2 x 10^7units/mg.
    Reinheit
    > 98 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product BTC Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    Betacellulin (BTC)
    Andere Bezeichnung
    Betacellulin (BTC Produkte)
    Hintergrund
    Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.
    Alternative Names: BTC protein, beta Cellulin protein
    Molekulargewicht
    9 kDa
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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