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Betacellulin Protein (BTC)

BTC Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN935244
  • Target Alle Betacellulin (BTC) Proteine anzeigen
    Betacellulin (BTC)
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 13
    • 5
    • 4
    • 2
    • 2
    Human
    Quelle
    • 15
    • 4
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Sequenz
    DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY
    Produktmerkmale
    Purified recombinant Human Betacellulin protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse Balb/3T3 cells is ? 0.05 ng/mL, corresponding to a specific activity of ? 2 x 10^7units/mg.
    Reinheit
    > 98 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product BTC Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    Betacellulin (BTC)
    Andere Bezeichnung
    Betacellulin (BTC Produkte)
    Synonyme
    BTC Protein, LOC100228121 Protein, probetacellulin Protein, Bcn Protein, betacellulin Protein, betacellulin, epidermal growth factor family member Protein, BTC Protein, LOC100228121 Protein, Btc Protein
    Hintergrund
    Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.
    Alternative Names: BTC protein, beta Cellulin protein
    Molekulargewicht
    9 kDa
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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