Defensin beta 4 Protein (DEFB4) (AA 33-47)

Produktnummer ABIN935250

Produktdetails

Target: Defensin beta 4 (DEFB4)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 33-47

Spezies: Human

Quelle: Escherichia coli (E. coli)

Sequenz: EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP

Produktmerkmale: Purified recombinant Human BD4 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-100.0 ng/mL.

Reinheit: > 98 % pure

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Antigendetails

Target: Defensin beta 4 (DEFB4)

Andere Bezeichnung: BD4 (DEFB4 Produkte)

Synonyme: BD-2 Protein, DEFB-2 Protein, DEFB102 Protein, DEFB2 Protein, DEFB4 Protein, HBD-2 Protein, SAP1 Protein, 2310001F05Rik Protein, BD-4 Protein, Defb2 Protein, Defb3 Protein, BNBD-4 Protein, BNBD4 Protein, defensin beta 4A Protein, defensin beta 4 Protein, defensin, beta 4A Protein, DEFB4A Protein, Defb4 Protein

Hintergrund: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence. beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta-defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. BD-4 is expressed in testis, stomach, uterus, neutrophils, thyroid, lung and kidney.
Alternative Names: BEFB4 protein, BD 4 protein, beta-defensin 104 protein, BD 4 protein, BD-4, BD-4 protein, BD 4, BD4, BD-4 protein

Molekulargewicht: 6.0 kDa