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GDF11 Protein

GDF11 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN935381
  • Target Alle GDF11 Proteine anzeigen
    GDF11 (Growth Differentiation Factor 11 (GDF11))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 6
    • 2
    • 2
    Human
    Quelle
    • 5
    • 2
    • 1
    Escherichia coli (E. coli)
    Sequenz
    NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS
    Produktmerkmale
    Purified recombinant Human GDF11 protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The expected ED50 for this effect is 0.08-0.10 µg/mL.
    Reinheit
    > 98 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product GDF11 Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.
    Buffer
    Supplied lyophilized with no additives.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    RT/-20 °C
  • Target
    GDF11 (Growth Differentiation Factor 11 (GDF11))
    Andere Bezeichnung
    GDF11 (GDF11 Produkte)
    Synonyme
    BMP-11 Protein, BMP11 Protein, Bmp11 Protein, GDF11 Protein, growth differentiation factor 11 Protein, GDF11 Protein, Gdf11 Protein, gdf11 Protein
    Hintergrund
    GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90 % identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same.
    Alternative Names: BMP-11 protein, GDF 11 protein, GDF-11 protein, GDF-11 protein, GDF-11, Growth/Differentiation Factor-11 protein, GDF11, GDF 11
    Molekulargewicht
    25 kDa
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