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GDF5 Protein

GDF5 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN935396
  • Target Alle GDF5 Proteine anzeigen
    GDF5 (Growth Differentiation Factor 5 (GDF5))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 6
    • 4
    • 2
    Human
    Quelle
    • 11
    • 1
    Escherichia coli (E. coli)
    Sequenz
    APSATRQGKR PSKNLKARCS RKALHVNFKD MGWDDWIIAP LEYEAFHCEG LCEFPLRSHL EPTNHAVIQT LMNSMDPEST PPTCCVPTRL SPISILFIDS ANNVVYKQYE DMVVESCGCR
    Produktmerkmale
    Purified recombinant Human GDF5 protein
    Expression System: E.coli
    Bioactivity: Induction of alkaline phosphatase activity in ATDC5 cells: EC50 = 40Nm.
    Reinheit
    > 98 % pure
    Top Product
    Discover our top product GDF5 Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Testdurchführung

    Protein quantitation was carried out by two independent methods1. UV spectroscopy at 280 nm using the absorbency value of 1.15 as the extinction coefficient for a 0.1 % (1 mg/mL) solution.
    2. Analysis by RP-HPLC, using a standard solution of GDF5 as a Reference Standard.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    RT/-20 °C
  • Target
    GDF5 (Growth Differentiation Factor 5 (GDF5))
    Andere Bezeichnung
    GDF5 (GDF5 Produkte)
    Synonyme
    CDMP1 Protein, gdf Protein, gdf-5 Protein, GDF5 Protein, BDA1C Protein, BMP14 Protein, LAP4 Protein, OS5 Protein, SYM1B Protein, SYNS2 Protein, Cdmp-1 Protein, bp Protein, brp Protein, Cdmp1 Protein, growth differentiation factor 5 L homeolog Protein, growth differentiation factor 5 Protein, gdf5.L Protein, GDF5 Protein, Gdf5 Protein
    Hintergrund
    GDF-5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.
    Alternative Names: BMP-14 protein, LAP4 protein, Growth Differentiation Factor 5 protein, GDF 5 protein, GDF-5 protein, Cartilage-derived morphogenetic protein-1 protein, GDF-5 protein, Radotermin protein, CDMP1 protein, GDF5 protein, GDF 5, BMP14 protein, Growth differentiation factor 5 protein, GDF-5 protein, CDMP-1 protein, SYNS2 protein, CDMP1 protein, GDF5, GDF-5
    Molekulargewicht
    26.8 kDa
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