GZMB Protein
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- Target Alle GZMB Proteine anzeigen
- GZMB (Granzyme B (GZMB))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Maus
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Quelle
- Baculovirus
- Sequenz
- IIGGHEVKPH SRPYMALLSI KDQQPEAICG GFLIREDFVL TAAHCEGSII NVTLGAHNIK EQEKTQQVIP MVKCIPHPDY NPKTFSNDIM LLKLKSKAKR TRAVRPLNLP RRNVNVKPGD VCYVAGWGRM APMGKYSNTL QEVELTVQKD RECESYFKNR YNKTNQICAG DPKTKRASFR GDSGGPLVCK KVAAGIVSYG YKDGSPPRAF TKVSSFLSWI KKTMKSS
- Produktmerkmale
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Purified recombinant Mouse Granzyme B protein
Expression System: Baculovirus
Bioactivity: Determined by its ability to cleave a synthetic chromogentic Granzyme B substrate. The expected specific activity , when using the Ac-IEPD-pNA substrate at 250C, is greater than 750 nM/min per µg of enzyme. - Reinheit
- > 98 % pure
- Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product GZMB Protein
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Granzyme B (GZMB) protein (His tag)
GZMB Spezies: Maus Wirt: Human Cells Recombinant > 85 % as determined by SDS-PAGE
Granzyme B (GZMB) (AA 148-247) protein (GST tag)GZMB Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) (AA 21-247) protein (GST tag)GZMB Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) (AA 1-247) protein (GST tag)GZMB Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- RT/-20 °C
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- Target
- GZMB (Granzyme B (GZMB))
- Andere Bezeichnung
- Granzyme B (GZMB Produkte)
- Hintergrund
- Granzyme B is a cysteine protease found in the cytoplasmic granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme B is required for the induction of target cell lysis, which occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms. Proteolytic cleavage of substrates by Granzyme B takes place primarily after aspartic acid residues. Recombinant Mouse.
- Molekulargewicht
- 28.9 kDa
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose
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