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IGFBPI Protein

IGFBPI Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 97 % pure Active
Produktnummer ABIN935566
  • Target Alle IGFBPI Proteine anzeigen
    IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Human
    Quelle
    • 18
    • 4
    • 3
    • 1
    Escherichia coli (E. coli)
    Sequenz
    MAPWQCAPCS AEKLALCPPV SASCSEVTRS AGCGCCPMCA LPLGAACGVA TARCARGLSC RALPGEQQPL HALTRGQGAC VQESDASAPH AAEAGSPESP ESTEITEEEL LDNFHLMAPS EEDHSILWDA ISTYDGSKAL HVTNIKKWKE PCRIELYRVV ESLAKAQETS GEEISKFYLP NCNKNGFYHS RQCETSMDGE AGLCWCVYPW NGKRIPGSPE IRGDPNCQIY FNVQN
    Produktmerkmale
    Purified recombinant Human IGF BP1 protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by its ability to inhibit IGF-I induced proliferation of MCF-7 is ? 0.5 µg/mL in the presence of 6 ng/mL of human IGF-I.
    Reinheit
    > 97 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IGFBPI Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    RT/-20 °C
  • Target
    IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))
    Andere Bezeichnung
    IGF BP1 (IGFBPI Produkte)
    Hintergrund
    IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, deciduas, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds to both IGF-I and IGF-II with equal affinity.
    Alternative Names: IGF BP-1, IGF BP-1 protein, IGF BP 1 protein, PP12 protein, IGF BP 1, IBP-1 protein, IGF BP1, Insulin-like Growth Factor-Binding Protein 1 protein, IGF BP-1 protein, Placenta Protein 12 protein
    Molekulargewicht
    25.4 kDa
    Pathways
    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Growth Factor Binding
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