Purified recombinant Mouse MCP1 protein Expression System: E.coli Bioactivity: Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/mL.
CCL2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Reconstitute in sterile water to 0.1-1.0 mg/mL. Allow to set for at least 30 minutes.
Buffer
Supplied lyophilized with no additives.
Konservierungsmittel
Without preservative
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
RT/-20 °C
Bogen, Dina, Gear, Levine: "Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican." in: Neuroscience, Vol. 159, Issue 2, pp. 780-6, (2009) (PubMed).
Frøyland, Pedersen, Kvissel, Almaas, Pharo, Skålhegg, Mollnes, Rootwelt: "Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons." in: Brain research, Vol. 1113, Issue 1, pp. 64-73, (2006) (PubMed).
The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Alternative Names: MCP-1 protein, MCP 1, MCP1, MCP-1 protein, MCP-1 protein, MCP 1 protein, Monocyte Chemotactic Protein-1 protein, MCP-1, CCL2 protein