ALOX5 Protein

Produktnummer ABIN935606

Produktdetails

Target: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Baculovirus

Produktmerkmale: Purified recombinant Human 5-Lipoxygenase protein
Expression System: Baculovirus
Bioactivity: 20 units/mg protein - One unit is defined as the amount of enzyme that consumes 1.0 nmol of oxygen per min at 25 °C in 50 mM Tris-HCl, 100 uM arachidonate, 2 mM CaCl2, 1 mM ATP, 250 uM oxygen. Oxygen consumption can be measured using a oxygraph equipped with a Clark oxygen electrode.

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 50 mM Tris containing 0 mM EDTA, pH 8.0.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -80 °C

Antigendetails

Target: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Andere Bezeichnung: 5-Lipoxygenase (ALOX5 Produkte)

Hintergrund: 5-lipoxygenase (5-LO) catalyzes the formation of 5(S)-HpETE from arachidonic acid and its subsequent conversion to leukotriene A4. It is localized in the cytosol of resting human and rat peripheral blood neutrophils, whereas it is found in the nucleus in rat basophilic leukemia cells and human alveolar macrophages. Upon stimulation of the cell, 5-LO translocates to the nuclear membrane where it is found in association with 5-LO activating protein (FLAP) and with the 85 kDa cPLA2.
Alternative Names: 5-Lipoxygenase Antigen, 5 Lipoxygenase Recombinant Protein

Molekulargewicht: 78 kDa