CLCF1 Protein

Produktnummer ABIN935688

Produktdetails

Target: CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Sequenz: MLNRTGDPGP GPSIQKTYDL TRYLEHQLRS LAGTYLNYLG PPFNEPDFNP PRLGAETLPR ATVDLEVWRS LNDKLRLTQN YEAYSHLLCY LRGLNRQAAT AELRRSLAHF CTSLQGLLGS IAGVMAALGY PLPQPLPGTE PTWTPGPAHS DFLQKMDDFW LLKELQTWLW RSAKDFNRLK KKMQPPAAAV TLHLGAHGF

Produktmerkmale: Purified recombinant Human NNT1 protein
Expression System: E.coli
Bioactivity: NT-1/BCSF-3 weakly supports chick E8 DRG neurite outgrowth at a concentration of 1.0 ng/mL.

Reinheit: > 98 % pure

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Antigendetails

Target: CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))

Andere Bezeichnung: NNT1 (CLCF1 Produkte)

Synonyme: clc Protein, nr6 Protein, bsf3 Protein, nnt1 Protein, ciss2 Protein, CLCF1 Protein, BSF-3 Protein, BSF3 Protein, CISS2 Protein, CLC Protein, NNT-1 Protein, NNT1 Protein, NR6 Protein, Bsf3 Protein, Clc Protein, cardiotrophin like cytokine factor 1 Protein, cardiotrophin-like cytokine factor 1 Protein, clcf1 Protein, CLCF1 Protein, Clcf1 Protein

Hintergrund: NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member beta (LIFR-beta) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM.
Alternative Names: NNT-1 protein, NNT-1 protein, Novel Neurtrophin-1/B-Cell Stimulating Factor-3 protein, Cardiotrophin-like cytokine protein, NNT 1, NNT 1 protein, NNT1, NNT-1

Molekulargewicht: 22.4 kDa

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response