TIMP2 Protein
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- Target Alle TIMP2 Proteine anzeigen
- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- MCSCSPVHPQ QAFCNADVVI RAKAVSEKEV DSGNDIYGNP IKRIQYEIKQ IKMFKGPEKD IEFIYTAPSS AVCGVSLDVG GKKEYLIAGK AEGDGKMHIT LCDFIVPWDT LSTTQKKSLN HRYQMGCECK ITRCPMIPCY ISSPDECLWM DWVTEKNING HQAKFFACIK RSDGSCAWYR GAAPPKQEFL DIEDP
- Produktmerkmale
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Purified recombinant Human TIMP2 protein
Expression System: E.coli
Bioactivity: TIMP-2 activity was measured by its ability to inhibit human MMP-1 induced hydrolysis of a chromogenic peptide substrate at room temperature. Half maximal inhibition was obtained at a TIMP-2 concentration of approximately 0.5 µg/mL, when using an MMP-1 concentration of 1.6 µg/mL. - Reinheit
- > 95 % pure
- Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product TIMP2 Protein
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Metalloproteinase Inhibitor 2 (TIMP2) protein (His tag)
TIMP2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Metalloproteinase Inhibitor 2 (TIMP2) (AA 27-220) protein (His tag)TIMP2 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Metalloproteinase Inhibitor 2 (TIMP2) protein (Fc Tag)TIMP2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Metalloproteinase Inhibitor 2 (TIMP2) (AA 27-220) protein (GST tag)TIMP2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Metalloproteinase Inhibitor 2 (TIMP2) (AA 30-220), (partial) protein (GST tag)TIMP2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 90 % ELISA
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
- Andere Bezeichnung
- TIMP2 (TIMP2 Produkte)
- Hintergrund
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TIMP-2 is an extracellular inhibitor of MMPs including MMP1, 2, 3, 7, 8, 9, 10, 12, 13, 14, 15, 16 and 19. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP-2 can also act through an MMP-independent mechanism inhibiting endothelial cell proliferation in vitro and demonstrates anti-angiogenic activities in vivo.
Alternative Names: TIMP 2 protein, Tissue inhibitor of metalloproteinases 2 protein, CSC-21K protein, TIMP2, TIMP-2 protein, TIMP-2 protein, TIMP-2, TIMP 2 - Molekulargewicht
- 21.8 kDa
- Pathways
- cAMP Metabolic Process
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