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Angiostatin Protein (ANG)

ANG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active
Produktnummer ABIN987759
  • Target Alle Angiostatin (ANG) Proteine anzeigen
    Angiostatin (ANG)
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 2
    • 2
    • 1
    Human
    Quelle
    • 5
    Escherichia coli (E. coli)
    Sequenz
    VYLSECKTGN GKNYRGTMSK TKNGITCQKW SSTSPHRPRF SPATHPSEGL EENYCRNPDN DPQGPWCYTT DPEKRYDYCD ILECEEECMH CSGENYDGKI SKTMSGLECQ AWDSQSPHAH GYIPSKFPNK NLKKNYCRNP DRELRPWCFT TDPNKRWELC DIPRCTTPPP SSGPTYQCLK GTGENYRGNV AVTVSGHTCQ HWSAQTPHTH NRTPENFPCK NLDENYCRNP DGKRAPWCHT TNSQVRWEYC KIPSCDSS
    Produktmerkmale
    Fully biologically active when compared to standard. The activity is assayed on anti-proliferation and anti-migration of endothelial cells in vitro and anti-angiogenesis in vivo. The specific activity of anti-migration of endothelial cells in vitro is 0.55×105 Units/mg.
    Reinheit
    > 95 % by SDS-PAGE and HPLC analyses.
    Endotoxin-Niveau
    Level Less than 1EU/µg of rHuAngiostatin as determined by LAL method
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
    Lagerung
    4 °C
  • Target
    Angiostatin (ANG)
    Andere Bezeichnung
    Angiostatin K1-3 (ANG Produkte)
    Synonyme
    ALS9 Protein, HEL168 Protein, RNASE4 Protein, RNASE5 Protein, LPA Protein, AI649309 Protein, Pg Protein, Ab1-346 Protein, AI385586 Protein, Ang1 Protein, Rnase5 Protein, Rnase5a Protein, angiogenin Protein, plasminogen Protein, angiogenin, ribonuclease, RNase A family, 5 Protein, ANG Protein, PLG Protein, Plg Protein, Ang Protein
    Hintergrund
    Angiostatin K1-3 is a ~30 kDa fragment of plasminogen that has been shown to act as a potent inhibitor of angiogenesis and tumor growth in vitro and in vivo. Recombinant angiostatin is expressed in E. coli. Synonym: Angiostatin K1-3, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM NaAc, pH5.5, 4% mannitol.
    Molekulargewicht
    Approximately 30.0 KDa, a single non-glycosylated polypeptide chain containing 259 amino acids.
    Pathways
    Lipid Metabolism
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