IL-33 Protein
-
- Target Alle IL-33 (IL33) Proteine anzeigen
- IL-33 (IL33) (Interleukin 33 (IL33))
- Biologische Aktivität
- Active
-
Spezies
- Human
-
Quelle
- Escherichia coli (E. coli)
- Sequenz
- MSITGISPIT EYLASLSTYN DQSITFALED ESYEIYVEDL KKDEKKDKVL LSYYESQHPS NESGDGVDGK MLMVTLSPTK DFWLHANNKE HSVELHKCEK PLPDQAFFVL HNMHSNCVSF ECKTDPGVFI GVKDNHLALI KVDSSENLCT ENILFKLSE
- Produktmerkmale
- Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ≤0.05ng/ml, corresponding to a specific activity of ≥2.0×107units/mg.
- Reinheit
- > 97 % by SDS-PAGE and HPLC analyses.
- Endotoxin-Niveau
- Level Less than 1EU/µg of rHuIL-33 as determined by LAL method
- Top Product
- Discover our top product IL33 Protein
-
Interleukin 33 (IL33) (AA 112-270) protein
IL33 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 33 (IL33) (AA 109-270) (Active) protein (His tag)IL33 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 33 (IL33) (AA 109-270) protein (His tag)IL33 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 33 (IL33) (AA 109-264) protein (His tag)IL33 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 33 (IL33) (AA 1-270) protein (GST tag)IL33 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 33 (IL33) (AA 171-269) protein (GST tag)IL33 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 33 (IL33) protein (His tag)IL33 Spezies: Rhesusaffen Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Interleukin 33 (IL33) (AA 109-270) (Active) protein (His tag)IL33 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
- Lagerung
- 4 °C
-
- Target
- IL-33 (IL33) (Interleukin 33 (IL33))
- Andere Bezeichnung
- Interleukin-33 (IL-33) (IL33 Produkte)
- Synonyme
- IL33 Protein, C9orf26 Protein, DVS27 Protein, IL1F11 Protein, NF-HEV Protein, NFEHEV Protein, RP11-575C20.2 Protein, 9230117N10Rik Protein, Il-33 Protein, Il1f11 Protein, RGD1311155 Protein, interleukin 33 Protein, IL33 Protein, Il33 Protein
- Hintergrund
- IL33, also known as NFHEV and DVS 27, is a 30 kDa proinflammatory protein that may also regulate gene transcription. IL33 is constitutively expressed in smooth muscle and airway epithelia. It is upregulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL1ª or IL1beta stimulation. IL-33 shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Synonym: Interleukin-33 (IL-33), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH7.4.
- Molekulargewicht
- Approximately 17.9 kDa, a single non-glycosylated polypeptide chain containing 160 amino acids.
- Pathways
- Production of Molecular Mediator of Immune Response
-
