PSMB8 Produkte
(Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))
Kategorien
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified\; both isoforms are processed to yield the same mature subunit. [provided by RefSeq, Jul 2008].
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Ausgewählte PSMB8 Kategorien
PSMB8 Antikörper
High quality antibodies with extensive validation data.
PSMB8 ELISA Kits
Reliable ELISA kits for a wide range of species.
PSMB8 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PSMB8 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA, ICC
Validierungen
- (2)
- (6)
Kat. Nr.
ABIN969371
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IP, IF, IHC (p)
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN562483
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7440236
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PSMB8 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962229
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958899
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958900
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PSMB8 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316595
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316593
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN2131388
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PSMB8 Produkten
: "The immunoproteasome catalytic β5i subunit regulates cardiac hypertrophy by targeting the autophagy protein ATG5 for degradation." in: Science advances, Vol. 5, Issue 5, pp. eaau0495, (2020) (PubMed).: "Predicting and validating the pathway of Wnt3a-driven suppression of osteoclastogenesis." in: Cellular signalling, Vol. 26, Issue 11, pp. 2358-69, (2014) (PubMed).
: "Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease." in: Cell death and differentiation, Vol. 18, Issue 6, pp. 1071-81, (2011) (PubMed).
: "PSMB8 (LMP7) but not PSMB9 (LMP2) gene polymorphisms are associated to pigeon breeder's hypersensitivity pneumonitis." in: Respiratory medicine, Vol. 104, Issue 6, pp. 889-94, (2010) (PubMed).
: "Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells." in: Neoplasia (New York, N.Y.), Vol. 12, Issue 7, pp. 550-61, (2010) (PubMed).
: "The early marginal zone B cell-initiated T-independent type 2 response resists the proteasome inhibitor bortezomib." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 9, pp. 5637-47, (2010) (PubMed).
: "Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma." in: Genes, chromosomes & cancer, Vol. 48, Issue 5, pp. 410-8, (2009) (PubMed).
: "Variation in HLA class I antigen-processing genes and susceptibility to human papillomavirus type 16-associated cervical cancer." in: The Journal of infectious diseases, Vol. 197, Issue 3, pp. 371-81, (2008) (PubMed).
: "Overexpression of the proteasome subunits LMP2, LMP7, and MECL-1, but not PA28 alpha/beta, enhances the presentation of an immunodominant lymphocytic choriomeningitis virus T cell epitope." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 2, pp. 768-78, (2000) (PubMed).
Synonyme und alternative Namen zu PSMB8
proteasome subunit beta 8 (PSMB8), proteasome subunit beta 8A (psmb8a), proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) (Psmb8), proteasome subunit beta 8 (Psmb8), ALDD, ATP6V0D2, D6S216, D6S216E, JMP, Lmp-7, LMP7, lmp7, Lmp7, macropain, NKJO, prosome, PSMB5i, RING10, Ring10Bezeichner auf Proteinebene für PSMB8
- large multifunctional peptidase 7
- low molecular mass protein 7
- low molecular weight protein 7
- macropain subunit C13
- multicatalytic endopeptidase complex subunit C13
- protease component C13
- proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
- proteasome catalytic subunit 3i
- proteasome component C13
- proteasome subunit Y2
- proteasome subunit beta 5i
- proteasome subunit beta type-8
- proteasome-related gene 7
- really interesting new gene 10 protein
- MHC class II DO beta
- proteasome subunit beta-5i
- proteasome (prosome, macropain) subunit, beta type, 8
- large multifunctional protease 7
- proteosome (prosome, macropain) subunit, beta type 8
- MC13 (LMP7)
- proteasome subunit MC13
- proteosome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
- proteosome beta 8 subunit
- low molecular mass polypeptide 7
- proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
- proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7)
- proteasome beta 8 subunit
- proteasome subunit LMP7
- macropain
- proteasome subunit, beta type 8
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