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PSMD11 Produkte

(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))

Kategorien

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012].

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Ausgewählte PSMD11 Kategorien

PSMD11 Antikörper

High quality antibodies with extensive validation data.

PSMD11 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PSMD11 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7142202
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN389306
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IF, ICC
Validierungen
  • (2)
Kat. Nr. ABIN6257765
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PSMD11 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6210729
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PSMD11 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316623
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN2131390
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7479249
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PSMD11 Produkten

Nath, Yu, Gipson, Marsh, Yoshidome, Robins, Todi, Housman, Lieberman: "Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction." in: The Journal of clinical investigation, Vol. 128, Issue 8, pp. 3630-3641, (2018) (PubMed).

Tsakiri, Gaboriaud-Kolar, Iliaki, Tchoumtchoua, Papanagnou, Chatzigeorgiou, Tallas, Mikros, Halabalaki, Skaltsounis, Trougakos: "The Indirubin Derivative 6-Bromoindirubin-3'-Oxime Activates Proteostatic Modules, Reprograms Cellular Bioenergetic Pathways, and Exerts Antiaging Effects." in: Antioxidants & redox signaling, (2017) (PubMed).

Welk, Coux, Kleene, Abeza, Trümbach, Eickelberg, Meiners: "Inhibition of Proteasome Activity Induces Formation of Alternative Proteasome Complexes." in: The Journal of biological chemistry, Vol. 291, Issue 25, pp. 13147-59, (2016) (PubMed).

Vilchez, Morantte, Liu, Douglas, Merkwirth, Rodrigues, Manning, Dillin: "RPN-6 determines C. elegans longevity under proteotoxic stress conditions." in: Nature, Vol. 489, Issue 7415, pp. 263-8, (2012) (PubMed).

Vilchez, Boyer, Morantte, Lutz, Merkwirth, Joyce, Spencer, Page, Masliah, Berggren, Gage, Dillin: "Increased proteasome activity in human embryonic stem cells is regulated by PSMD11." in: Nature, Vol. 489, Issue 7415, pp. 304-8, (2012) (PubMed).

Liu, Lee, Krummey, Lu, Cai, Lenardo: "The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease." in: Nature immunology, Vol. 12, Issue 11, pp. 1063-70, (2011) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Sklirou, Gaboriaud-Kolar, Papassideri, Skaltsounis, Trougakos et al.: "6-bromo-indirubin-3'-oxime (6BIO), a Glycogen synthase kinase-3β inhibitor, activates cytoprotective cellular modules and suppresses cellular senescence-mediated biomolecular damage in human ..." in: Scientific reports, Vol. 7, Issue 1, pp. 11713 (PubMed).

Synonyme und alternative Namen zu PSMD11

proteasome 26S subunit, non-ATPase 11 (PSMD11), proteasome 26S subunit, non-ATPase 11b (psmd11b), proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 (Psmd11), proteasome 26S subunit, non-ATPase 11 (Psmd11), 1700089D09Rik, 1810019E17Rik, 2610024G20Rik, 2810055C24Rik, C78232, p44.5, P44.5, psmd11, Rpn6, S9, wu:fb55b06, zgc:56580, zgc:77763

Bezeichner auf Proteinebene für PSMD11

  • proteasome 26S non-ATPase subunit 11
  • 26S proteasome non-ATPase regulatory subunit 11B
  • 26S proteasome regulatory subunit RPN6-B
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
  • 26S proteasome non-ATPase regulatory subunit 11
  • 26S proteasome regulatory subunit 9
  • 26S proteasome regulatory subunit RPN6
  • 26S proteasome regulatory subunit S9
  • 26S proteasome regulatory subunit p44.5
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