PSMD2 Produkte
(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 2 (PSMD2))
Kategorien
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008].
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Ausgewählte PSMD2 Kategorien
PSMD2 Antikörper
High quality antibodies with extensive validation data.
PSMD2 ELISA Kits
Reliable ELISA kits for a wide range of species.
PSMD2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PSMD2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (8)
Kat. Nr.
ABIN7439738
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (6)
Kat. Nr.
ABIN3015813
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Dog, Human, Monkey, Mouse, Rat
Applikation
WB, IF, IHC, IHC (p)
Validierungen
- (11)
Kat. Nr.
ABIN1500479
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PSMD2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN5648250
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Chicken
Analytical Method
Validierungen
Kat. Nr.
ABIN1773469
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Sheep
Analytical Method
Validierungen
Kat. Nr.
ABIN1774693
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PSMD2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316633
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7405741
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3094827
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PSMD2 Produkten
: "Acute ethanol exposure reduces serotonin receptor 1A internalization by increasing ubiquitination and degradation of β-arrestin2." in: The Journal of biological chemistry, Vol. 294, Issue 38, pp. 14068-14080, (2019) (PubMed).: "The transition zone protein Rpgrip1l regulates proteasomal activity at the primary cilium." in: The Journal of cell biology, Vol. 210, Issue 1, pp. 115-33, (2015) (PubMed).
: "Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways." in: The Journal of biological chemistry, Vol. 289, Issue 1, pp. 510-9, (2014) (PubMed).
: "Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain." in: Biochimica et biophysica acta, Vol. 1832, Issue 8, pp. 1249-59, (2013) (PubMed).
: "NAK is recruited to the TNFR1 complex in a TNFalpha-dependent manner and mediates the production of RANTES: identification of endogenous TNFR-interacting proteins by a proteomic approach." in: The Journal of biological chemistry, Vol. 279, Issue 51, pp. 53266-71, (2004) (PubMed).
Synonyme und alternative Namen zu PSMD2
26S proteasome non-ATPase regulatory subunit 2 (psmD2), 26S proteasome regulatory subunit S2 (NAEGRDRAFT_83014), 26S proteasome regulatory subunit S2 (DICPUDRAFT_55026), proteasome 26S subunit, non-ATPase 2 (psmd2), proteasome 26S subunit, non-ATPase 2 L homeolog (psmd2.L), proteasome 26S subunit, non-ATPase 2 S homeolog (psmd2.S), proteasome 26S subunit, non-ATPase 2 (PSMD2), proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 (psmd2), proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 (Psmd2), proteasome 26S subunit, non-ATPase 2 (Psmd2), 9430095H01Rik, AA407121, DDBDRAFT_0192101, DDBDRAFT_0232978, DDB_0192101, DDB_0232978, MGC83233, MGC97650, P97, psmd2, PSMD2, RPN1, S2, TEG-190, Tex190, TRAP2, zgc:65921Bezeichner auf Proteinebene für PSMD2
- 26S proteasome regulatory subunit S2
- 26S proteasome non-ATPase regulatory subunit 2
- 26s proteasome regulatory subunit S2-like protein
- proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
- proteasome 26S non-ATPase subunit 2
- 55.11 protein
- TNFR-associated protein 2
- protein 55.11
- tumor necrosis factor type 1 receptor-associated protein 2
- 26S proteasome regulatory subunit RPN1
- 26S proteasome subunit p97
- testis expressed gene 190
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