PTPN12 Produkte
(Protein Tyrosine Phosphatase G1 (PTPN12))
Kategorien
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].
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Ausgewählte PTPN12 Kategorien
PTPN12 Antikörper
High quality antibodies with extensive validation data.
PTPN12 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PTPN12 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, IF
Validierungen
- (14)
Kat. Nr.
ABIN7075292
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN2855422
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7239389
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene PTPN12 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6730261
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PTPN12 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124676
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316826
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316828
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PTPN12 Produkten
: "Tyrosine-protein phosphatase non-receptor type 12 expression is a good prognostic factor in resectable non-small cell lung cancer." in: Oncotarget, Vol. 6, Issue 13, pp. 11704-13, (2015) (PubMed).: "PTPN12 promotes resistance to oxidative stress and supports tumorigenesis by regulating FOXO signaling." in: Oncogene, Vol. 33, Issue 8, pp. 1047-54, (2014) (PubMed).
: "Macrophage fusion is controlled by the cytoplasmic protein tyrosine phosphatase PTP-PEST/PTPN12." in: Molecular and cellular biology, Vol. 33, Issue 12, pp. 2458-69, (2013) (PubMed).
Synonyme und alternative Namen zu PTPN12
protein tyrosine phosphatase, non-receptor type 12 (PTPN12), protein tyrosine phosphatase, non-receptor type 12 (Ptpn12), P19-PTP, PTP-P19, PTP-PEST, PTPG1, Ptpg1, RKPTPBezeichner auf Proteinebene für PTPN12
- protein-tyrosine phosphatase G1
- tyrosine-protein phosphatase non-receptor type 12
- MPTP-PEST
- protein-tyrosine phosphatase P19
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