PTPN2 Produkte
(Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))
Kategorien
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011].
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Ausgewählte PTPN2 Kategorien
PTPN2 Antikörper
High quality antibodies with extensive validation data.
PTPN2 ELISA Kits
Reliable ELISA kits for a wide range of species.
PTPN2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PTPN2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (8)
Kat. Nr.
ABIN3022585
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7444958
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN657234
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene PTPN2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4884735
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6386214
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PTPN2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316834
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Baculovirus infected Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN7197593
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7419406
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PTPN2 Produkten
: "Protein Tyrosine Phosphatase Nonreceptor Type 2 (PTPN2), an Important Regulator of IL-6 Production in Rheumatoid Arthritis Synovial Fibroblasts." in: Arthritis & rheumatology (Hoboken, N.J.), (2015) (PubMed).: "Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2." in: Cell death & disease, Vol. 4, pp. e588, (2013) (PubMed).
: "T-cell protein tyrosine phosphatase is a key regulator in immune cell signaling: lessons from the knockout mouse model and implications in human disease." in: Immunological reviews, Vol. 228, Issue 1, pp. 325-41, (2009) (PubMed).
: "TC-PTP-deficient bone marrow stromal cells fail to support normal B lymphopoiesis due to abnormal secretion of interferon-{gamma}." in: Blood, Vol. 109, Issue 10, pp. 4220-8, (2007) (PubMed).
: "Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP." in: Molecular and cellular biology, Vol. 23, Issue 6, pp. 2096-108, (2003) (PubMed).
: "Gr-1+ myeloid cells lacking T cell protein tyrosine phosphatase inhibit lymphocyte proliferation by an IFN-gamma- and nitric oxide-dependent mechanism." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 2, pp. 726-32, (2003) (PubMed).
: "Identification of a nuclear Stat1 protein tyrosine phosphatase." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5662-8, (2002) (PubMed).
Synonyme und alternative Namen zu PTPN2
protein tyrosine phosphatase, non-receptor type 2 (PTPN2), protein tyrosine phosphatase, non-receptor type 2 (Ptpn2), protein tyrosine phosphatase, non-receptor type 2 S homeolog (ptpn2.S), protein tyrosine phosphatase, non-receptor type 2, b (ptpn2b), protein tyrosine phosphatase, non-receptor type 2, a (ptpn2a), protein tyrosine phosphatase, non-receptor type 2 L homeolog (ptpn2.L), AI325124, cb806, hm:zeh1546, PTN2, ptn2, PTP-1B, ptpn2, ptpn2l, PTPT, Ptpt, ptpt, TC-PTP, tc-ptp, TCELLPTP, tcellptp, TCPTP, tcptp, wu:fc10h07, zgc:55339, zgc:63623, zgc:76973Bezeichner auf Proteinebene für PTPN2
- T-cell protein tyrosine phosphatase
- tyrosine-protein phosphatase non-receptor type 2
- MPTP
- T cell protein-tyrosine phosphatase
- protein-tyrosine phosphatase PTP-2
- protein-tyrosine phosphatase PTP-S
- phosphoprotein phosphatase
- protein tyrosine phosphatase 1B
- protein tyrosine phosphatase, non-receptor type 2, like
- protein tyrosine phosphatase, non-receptor type 2, a
- protein tyrosine phosphatase, non-receptor type 2 L homeolog
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