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PTPRA Produkte

(Protein tyrosine Phosphatase, Receptor Type, A (PTPRA))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008].

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Ausgewählte PTPRA Kategorien

PTPRA Antikörper

High quality antibodies with extensive validation data.

PTPRA ELISA Kits

Reliable ELISA kits for a wide range of species.

PTPRA Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PTPRA Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (4)
Kat. Nr. ABIN1682399
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation IHC
Validierungen
  • (3)
Kat. Nr. ABIN7260017
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Bat, Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit
Applikation IHC, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN1049270
Menge 50 μg
Datenblatt Datenblatt

Empfohlene PTPRA ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951512
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1154921
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1154922
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PTPRA Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7419442
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7419745
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
Kat. Nr. ABIN7509248
Menge 25 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PTPRA Produkten

Wu, Kao, Li, Chi, Lin: "Protein tyrosine-phosphatase expression profiling in gastric cancer tissues." in: Cancer letters, Vol. 242, Issue 1, pp. 95-103, (2006) (PubMed).

Yahiro, Wada, Nakayama, Kimura, Ogushi, Niidome, Aoyagi, Yoshino, Yonezawa, Moss, Hirayama: "Protein-tyrosine phosphatase alpha, RPTP alpha, is a Helicobacter pylori VacA receptor." in: The Journal of biological chemistry, Vol. 278, Issue 21, pp. 19183-9, (2003) (PubMed).

Zhang, Kondrikov, Yuan, Lin, Hansen, Lin: "Receptor protein tyrosine phosphatase alpha signaling is involved in androgen depletion-induced neuroendocrine differentiation of androgen-sensitive LNCaP human prostate cancer cells." in: Oncogene, Vol. 22, Issue 43, pp. 6704-16, (2003) (PubMed).

Kapp, Metzinger, Kellerer, Häring, Lammers: "The protein tyrosine phosphatase alpha modifies insulin secretion in INS-1E cells." in: Biochemical and biophysical research communications, Vol. 311, Issue 2, pp. 361-4, (2003) (PubMed).

Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

Zheng, Pallen: "Expression of receptor-like protein tyrosine phosphatase alpha in rat embryo fibroblasts activates mitogen-activated protein kinase and c-Jun." in: The Journal of biological chemistry, Vol. 269, Issue 37, pp. 23302-9, (1994) (PubMed).

Zheng, Wang, Pallen: "Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase." in: Nature, Vol. 359, Issue 6393, pp. 336-9, (1992) (PubMed).

Sap, DEustachio, Givol, Schlessinger: "Cloning and expression of a widely expressed receptor tyrosine phosphatase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 16, pp. 6112-6, (1990) (PubMed).

Synonyme und alternative Namen zu PTPRA

protein tyrosine phosphatase, receptor type A (PTPRA), protein tyrosine phosphatase, receptor type A (ptpra), protein tyrosine phosphatase, receptor type, A (PTPRA), protein tyrosine phosphatase, receptor type, A (Ptpra), protein tyrosine phosphatase, receptor type, A (ptpra), protein tyrosine phosphatase, receptor type A S homeolog (ptpra.S), heptp, HEPTP, hlpr, HLPR, hptpa, HPTPA, hptpalpha, HPTPalpha, lrp, LRP, ptpa, PTPA, Ptpa, ptpa-a, Ptpalpha, PTPRA, ptprl2, PTPRL2, r-ptp-alpha, R-PTP-alpha, rptpa, RPTPA, Rptpalpha, RPTP[a], Rptra, Rptralpha, zf-RPTP[a]

Bezeichner auf Proteinebene für PTPRA

  • protein tyrosine phosphatase, receptor type, A
  • receptor-type tyrosine-protein phosphatase alpha-like
  • Leukocyte common antigen-related peptide (protein tyrosine phosphate)
  • PTPLCA-related phosphatase
  • PTPase-alpha
  • protein tyrosine phosphatase, receptor type, alpha polypeptide
  • protein-tyrosine phosphatase alpha
  • receptor-type tyrosine-protein phosphatase alpha
  • tyrosine phosphatase alpha
  • LCA-related phosphatase
  • PTPTY-28
  • R-PTP-alpha
  • protein tyrosine phosphatase alpha
  • protein tyrosine phosphatase receptor type alpha
  • protein-tyrosine-phosphatase alpha
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