PTPRF Produkte
(Protein Tyrosine Phosphatase Receptor Type F (PTPRF))
Kategorien
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008].
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Ausgewählte PTPRF Kategorien
PTPRF Antikörper
High quality antibodies with extensive validation data.
PTPRF ELISA Kits
Reliable ELISA kits for a wide range of species.
PTPRF Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PTPRF Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ICC, IHC, IP
Validierungen
- (4)
Kat. Nr.
ABIN7444742
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, FACS
Validierungen
- (4)
Kat. Nr.
ABIN7193270
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7167505
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PTPRF ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969749
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958952
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6210120
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PTPRF Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316869
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7418794
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PTPRF Produkten
: "A new 12-gene diagnostic biomarker signature of melanoma revealed by integrated microarray analysis." in: PeerJ, Vol. 1, pp. e49, (2013) (PubMed).: "Trans-induced cis interaction in the tripartite NGL-1, netrin-G1 and LAR adhesion complex promotes development of excitatory synapses." in: Journal of cell science, Vol. 126, Issue Pt 21, pp. 4926-38, (2013) (PubMed).
: "Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases." in: The Journal of biological chemistry, Vol. 277, Issue 49, pp. 47263-9, (2002) (PubMed).
: "Regulation of Lck and Fyn tyrosine kinase activities by transmembrane protein tyrosine phosphatase leukocyte common antigen-related molecule." in: Molecular cancer research : MCR, Vol. 1, Issue 2, pp. 155-63, (2002) (PubMed).
: "Galpha(i2) enhances insulin signaling via suppression of protein-tyrosine phosphatase 1B." in: The Journal of biological chemistry, Vol. 276, Issue 43, pp. 39705-12, (2001) (PubMed).
: "Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 9, pp. 5187-92, (2001) (PubMed).
: "Use of an antisense strategy to dissect the signaling role of protein-tyrosine phosphatase alpha." in: The Journal of biological chemistry, Vol. 274, Issue 37, pp. 26105-12, (1999) (PubMed).
: "Leukocyte common antigen-related receptor-linked tyrosine phosphatase. Regulation of mRNA expression." in: The Journal of biological chemistry, Vol. 268, Issue 35, pp. 26503-11, (1994) (PubMed).
: "The SJL/J T cell response to both spontaneous and transplantable syngeneic reticulum cell sarcoma is mediated predominantly by the V beta 17a+ T cell clonotype." in: The Journal of experimental medicine, Vol. 168, Issue 5, pp. 1553-62, (1988) (PubMed).
Synonyme und alternative Namen zu PTPRF
protein tyrosine phosphatase, receptor type F (PTPRF), protein tyrosine phosphatase, receptor type, F (Ptprf), protein tyrosine phosphatase, receptor type, f, a (ptprfa), AA591035, LAR, LARFN5C, LARS, RPTP-LAR, zf-LARBezeichner auf Proteinebene für PTPRF
- LCA-homolog
- leukocyte antigen-related (LAR) PTP receptor
- leukocyte antigen-related tyrosine phosphatase
- leukocyte common antigen related
- protein tyrosine phosphatase, receptor type, F polypeptide
- receptor-linked protein-tyrosine phosphatase LAR
- receptor-type tyrosine-protein phosphatase F
- LAR
- protein tyrosine phosphatase receptor-type F
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