PTPRN Produkte
(Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
Kategorien
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010].
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Ausgewählte PTPRN Kategorien
PTPRN Antikörper
High quality antibodies with extensive validation data.
PTPRN ELISA Kits
Reliable ELISA kits for a wide range of species.
PTPRN Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PTPRN Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), IHC (fro), ICC
Validierungen
- (3)
Kat. Nr.
ABIN7439915
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN948357
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), IHC (fro), ICC
Validierungen
- (2)
Kat. Nr.
ABIN7444055
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PTPRN ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962149
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969757
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969756
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PTPRN Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124688
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124687
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316877
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PTPRN Produkten
: "Small cell lung cancer growth is inhibited by miR-342 through its effect of the target gene IA-2." in: Journal of translational medicine, Vol. 14, Issue 1, pp. 278, (2016) (PubMed).: "Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates." in: Journal of proteomics, Vol. 75, Issue 9, pp. 2611-20, (2012) (PubMed).
: "Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2." in: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4674-81, (2008) (PubMed).
: "ICA512 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 2, pp. 674-9, (2008) (PubMed).
: "RESP18, a homolog of the luminal domain IA-2, is found in dense core vesicles in pancreatic islet cells and is induced by high glucose." in: The Journal of endocrinology, Vol. 195, Issue 2, pp. 313-21, (2007) (PubMed).
: "High titer of autoantibodies to GAD identifies a specific phenotype of adult-onset autoimmune diabetes." in: Diabetes Care, Vol. 30, Issue 4, pp. 932-8, (2007) (PubMed).
: "ICA512(IA-2) epitope specific assays distinguish transient from diabetes associated autoantibodies." in: Journal of autoimmunity, Vol. 18, Issue 2, pp. 191-6, (2002) (PubMed).
Synonyme und alternative Namen zu PTPRN
protein tyrosine phosphatase, receptor type N (PTPRN), protein tyrosine phosphatase, receptor type, N (Ptprn), protein tyrosine phosphatase, receptor type N (Ptprn), protein tyrosine phosphatase, receptor type, Na (ptprna), protein tyrosine phosphatase, receptor type N L homeolog (ptprn.L), fc43c04, IA-2, Ia-2, ia-2, IA-2/PTP, IA2, ia2, ICA512, ica512, mIA-A, mKIAA4064, ptprn, R-PTP-N, r-ptp-n, wu:fc43c04Bezeichner auf Proteinebene für PTPRN
- ICA 512
- PTP IA-2
- islet cell antigen 2
- islet cell antigen 512
- islet cell autoantigen 3
- protein tyrosine phosphatase-like N
- receptor-type tyrosine-protein phosphatase-like N
- ICA512
- R-PTP-N
- islet cell autoantigen 512
- protein tyrosine phosphatase, receptor-type, N
- 105 kDa islet cell antigen
- BEM-3
- ICA105
- PTPLP
- brain-enriched membrane-associated protein tyrosine phosphatase
- insulinoma antigen-2
- receptor type N protein tyrosine phosphatase
- protein tyrosine phosphatase, receptor type, N
- protein tyrosine phosphatase, receptor type, Na
- protein tyrosine phosphatase, receptor type N L homeolog
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