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PYM Produkte

(Partner of Y14 and mago (WIBG))

Kategorien

Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post- transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions (By similarity).

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Ausgewählte PYM Kategorien

PYM Antikörper

High quality antibodies with extensive validation data.

PYM Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PYM Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN654666
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN6750448
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Bat, Cow, Dog, Horse, Human, Monkey, Pig, Xenopus laevis
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN6746847
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PYM Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1325328
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN1097293
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN2132576
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PYM Produkten

Li, Johnson, Truong, Kim, Weinbren, Dittmar, Shah, Von Dollen, Newton, Jang, Krogan, Cherry, Ramage: "Identification of antiviral roles for the exon-junction complex and nonsense-mediated decay in flaviviral infection." in: Nature microbiology, Vol. 4, Issue 6, pp. 985-995, (2019) (PubMed).

Sun, Boxer, Ransohoff, Siprashvili, Qu, Lopez-Pajares, Hollmig, Khavari: "CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation." in: Genes & development, Vol. 29, Issue 21, pp. 2225-30, (2015) (PubMed).

Synonyme und alternative Namen zu PYM

Partner of Y14 and Mago (Pym), Wibg protein (wibg), PYM homolog 1, exon junction complex associated factor L homeolog (pym1.L), PYM homolog 1, exon junction complex associated factor (PYM1), PYM homolog 1, exon junction complex associated factor (Pym1), PYM homolog 1, exon junction complex associated factor (pym1), A030010B05Rik, BEST:HL05757, CG10330, CG30176, Dmel\\CG30176, PYM, Pym, UD3, zgc:65891, zgc:77281

Bezeichner auf Proteinebene für PYM

  • CG30176-PA
  • undefined 3
  • wibg-PA
  • Protein wibg homolog
  • partner of Y14 and mago
  • protein wibg homolog
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