Pyruvate Dehydrogenase (Lipoamide) alpha 1 Produkte
(Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))
Kategorien
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010].
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Ausgewählte Pyruvate Dehydrogenase (Lipoamide) alpha 1 Kategorien
Pyruvate Dehydrogenase (Lipoamide) alpha 1 Antikörper
High quality antibodies with extensive validation data.
Pyruvate Dehydrogenase (Lipoamide) alpha 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Pyruvate Dehydrogenase (Lipoamide) alpha 1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Pyruvate Dehydrogenase (Lipoamide) alpha 1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7432574
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (6)
Kat. Nr.
ABIN518747
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF, IP
Validierungen
- (7)
Kat. Nr.
ABIN3023697
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Pyruvate Dehydrogenase (Lipoamide) alpha 1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969793
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959003
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959004
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Pyruvate Dehydrogenase (Lipoamide) alpha 1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314518
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7392011
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7392005
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Pyruvate Dehydrogenase (Lipoamide) alpha 1 Produkten
: "The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer." in: Cancer & metabolism, Vol. 7, pp. 1, (2019) (PubMed).: "Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions." in: Cell reports, Vol. 22, Issue 6, pp. 1509-1521, (2019) (PubMed).
: "ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLCβ3 Catalysis: Targeting It Eradicates Leukemia Stem Cells." in: Cell reports, Vol. 26, Issue 8, pp. 2166-2177.e9, (2019) (PubMed).
: "Loss of GCN5L1 in cardiac cells limits mitochondrial respiratory capacity under hyperglycemic conditions." in: Physiological reports, Vol. 7, Issue 8, pp. e14054, (2019) (PubMed).
: "The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA." in: The Journal of biological chemistry, Vol. 293, Issue 46, pp. 17676-17684, (2018) (PubMed).
: "Alcohol inhibits T-cell glucose metabolism and hepatitis in ALDH2-deficient mice and humans: roles of acetaldehyde and glucocorticoids." in: Gut, (2018) (PubMed).
: "The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle." in: JCI insight, Vol. 3, Issue 22, (2018) (PubMed).
: "MicroRNA-23a promotes colorectal cancer cell survival by targeting PDK4." in: Experimental cell research, Vol. 373, Issue 1-2, pp. 171-179, (2018) (PubMed).
: "MiR-494-3p regulates mitochondrial biogenesis and thermogenesis through PGC1-α signalling in beige adipocytes." in: Scientific reports, Vol. 8, Issue 1, pp. 15096, (2018) (PubMed).
: "Pathological consequences of MICU1 mutations on mitochondrial calcium signalling and bioenergetics." in: Biochimica et biophysica acta, Vol. 1864, Issue 6, pp. 1009-1017, (2017) (PubMed).
Synonyme und alternative Namen zu Pyruvate Dehydrogenase (Lipoamide) alpha 1
pyruvate dehydrogenase E1 alpha 1 subunit (PDHA1), pyruvate dehydrogenase E1 alpha 1 (Pdha1), pyruvate dehydrogenase E1 alpha 1 subunit (Pdha1), pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1), pyruvate dehydrogenase E1 alpha 1 subunit (pdha1), pyruvate dehydrogenase (lipoamide) alpha 1 pseudogene (LOC719277), 2-oxo acid dehydrogenase (VNG_RS07485), pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha (RR_RS04695), pyruvate dehydrogenase alpha subunit protein (pdhA1), pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit (pdhA1), precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit (PDHA1), pyruvate dehydrogenase (PDHA1), pyruvate dehydrogenase E1 alpha 1 subunit a (pdha1a), pyruvate dehydrogenase E1 alpha 1 subunit b (pdha1b), pyruvate dehydrogenase E1 component subunit alpha (NI36_RS05240), pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog (pdha1.S), im:6895726, NI36_05250, PDHA, pdha, Pdha-1, pdha1, Pdha1, pdha1-a, pdha1-b, PDHCE1A, pdhce1a, PHE1A, phe1a, wu:fd18b01, wu:fo96f03, wu:fp73b04, zgc:73271, zgc:86692, zgc:92705Bezeichner auf Proteinebene für Pyruvate Dehydrogenase (Lipoamide) alpha 1
- PDHE1-A type I
- pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
- pyruvate dehydrogenase complex, E1-alpha polypeptide 1
- pyruvate dehydrogenase E1alpha subunit
- pyruvate dehydrogenase E1 alpha 1
- pyruvate dehydrogenase E1 component alpha subunit
- pyruvate dehydrogenase alpha 1
- pyruvate dehydrogenase (lipoamide) alpha 1
- PdhA1
- pyruvate dehydrogenase alpha subunit
- pyruvate dehydrogenase E1 component subunit alpha
- pyruvate dehydrogenase alpha subunit protein
- pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit
- precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit
- pyruvate dehydrogenase
- Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
- pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial-like
- fp73b04
- pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog
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