RAB8A Produkte
(RAB8A, Member RAS Oncogene Family (RAB8A))
Kategorien
The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq, Jul 2008].
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Ausgewählte RAB8A Kategorien
RAB8A Antikörper
High quality antibodies with extensive validation data.
RAB8A ELISA Kits
Reliable ELISA kits for a wide range of species.
RAB8A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RAB8A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), FACS
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN1881723
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS, ICC
Validierungen
- (4)
Kat. Nr.
ABIN5542342
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (4)
Kat. Nr.
ABIN561805
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene RAB8A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969818
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Validierungen
Kat. Nr.
ABIN1154795
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Cow
Analytical Method
Validierungen
Kat. Nr.
ABIN1154790
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RAB8A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317201
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317203
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2730373
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RAB8A Produkten
: "Transcription factor EB‑mediated autophagy promotes dermal fibroblast differentiation and collagen production by regulating endoplasmic reticulum stress and autophagy‑dependent secretion." in: International journal of molecular medicine, Vol. 47, Issue 2, pp. 547-560, (2021) (PubMed).: "Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3." in: The Journal of cell biology, Vol. 211, Issue 3, pp. 587-604, (2015) (PubMed).
: "Drebrin E depletion in human intestinal epithelial cells mimics Rab8a loss of function." in: Human molecular genetics, Vol. 23, Issue 11, pp. 2834-46, (2014) (PubMed).
: "Levels of Rabs and WAVE family proteins associated with translocation of GLUT4 to the cell surface in endometria from hyperinsulinemic PCOS women." in: Human reproduction (Oxford, England), Vol. 25, Issue 11, pp. 2870-7, (2010) (PubMed).
: "Functional dissection of Rab GTPases involved in primary cilium formation." in: The Journal of cell biology, Vol. 178, Issue 3, pp. 363-9, (2007) (PubMed).
: "Rab27a: A key to melanosome transport in human melanocytes." in: The Journal of cell biology, Vol. 152, Issue 4, pp. 843-50, (2001) (PubMed).
: "Rab27a regulates the peripheral distribution of melanosomes in melanocytes." in: The Journal of cell biology, Vol. 152, Issue 4, pp. 795-808, (2001) (PubMed).
: "Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation." in: Molecular biology of the cell, Vol. 11, Issue 1, pp. 393-412, (2000) (PubMed).
: "Construction of a human full-length cDNA bank." in: Gene, Vol. 150, Issue 2, pp. 243-50, (1995) (PubMed).
: "A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells." in: The Journal of cell biology, Vol. 124, Issue 1-2, pp. 101-15, (1994) (PubMed).
Synonyme und alternative Namen zu RAB8A
rab8A protein (rab8A), Rab GTPase (rab8A), RAB8A, member RAS oncogene family (RAB8A), RAB8A, member RAS oncogene family (rab8a), RAB8A, member RAS oncogene family S homeolog (rab8a.S), RAB8A, member RAS oncogene family (Rab8a), AA409338, c-mel, DDBDRAFT_0206521, DDBDRAFT_0214885, DDB_0206521, DDB_0214885, HSH2D, mel, MEL, Mel, rab8, RAB8, Rab8, rab8A, zgc:162699Bezeichner auf Proteinebene für RAB8A
- rab8A protein
- hematopoietic SH2 domain containing
- ras-related protein Rab-8A
- RAB8A, member RAS oncogene family
- member RAS oncogene family
- Ras-related protein Rab-8A
- mel transforming oncogene (RAB8 homolog)
- mel transforming oncogene (derived from cell line NK14)
- mel transforming oncogene (derived from cell line NK14)- RAB8 homolog
- oncogene c-mel
- ras-associated protein RAB8
- RAB8, member RAS oncogene family
- cell line NK14 derived transforming oncogene
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