Raptor Produkte
(Regulatory Associated Protein of mTOR, Complex 1 (RPTOR))
Kategorien
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
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Ausgewählte Raptor Kategorien
Raptor Antikörper
High quality antibodies with extensive validation data.
Raptor ELISA Kits
Reliable ELISA kits for a wide range of species.
Raptor Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Raptor Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA
Validierungen
- (2)
- (3)
Kat. Nr.
ABIN1724920
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7269900
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7167652
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene Raptor ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969886
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5594983
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Raptor Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1318870
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1318872
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Raptor Produkten
: "Contractile activity-induced mitochondrial biogenesis and mTORC1." in: American journal of physiology. Cell physiology, Vol. 303, Issue 5, pp. C540-7, (2012) (PubMed).: "Raptor, a positive regulatory subunit of mTOR complex 1, is a novel phosphoprotein of the rDNA transcription machinery in nucleoli and chromosomal nucleolus organizer regions (NORs)." in: Cell cycle (Georgetown, Tex.), Vol. 10, Issue 18, pp. 3140-52, (2011) (PubMed).
: "Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: a phase 2 study." in: The Lancet. Oncology, Vol. 12, Issue 4, pp. 361-8, (2011) (PubMed).
: "Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations." in: PLoS genetics, Vol. 6, Issue 10, pp. e1001178, (2010) (PubMed).
: "mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 26, pp. 11823-8, (2010) (PubMed).
: "A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1." in: Molecular and cellular biology, Vol. 30, Issue 2, pp. 481-95, (2009) (PubMed).
: "ASCT2 silencing regulates mammalian target-of-rapamycin growth and survival signaling in human hepatoma cells." in: American journal of physiology. Cell physiology, Vol. 293, Issue 1, pp. C55-63, (2007) (PubMed).
: "Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation." in: Circulation research, Vol. 101, Issue 6, pp. 560-9, (2007) (PubMed).
: "Inhibition of mammalian target of rapamycin signaling by 2-(morpholin-1-yl)pyrimido[2,1-alpha]isoquinolin-4-one." in: The Journal of biological chemistry, Vol. 282, Issue 33, pp. 24463-70, (2007) (PubMed).
: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, (2006) (PubMed).
Synonyme und alternative Namen zu Raptor
regulatory associated protein of MTOR complex 1 (RPTOR), regulatory associated protein of MTOR, complex 1 (Rptor), regulatory associated protein of MTOR, complex 1 L homeolog (rptor.L), regulatory associated protein of MTOR, complex 1 (rptor), 4932417H02Rik, KOG1, Mip1, mKIAA1303, Rap, Raptor, raptor, RGD1311784Bezeichner auf Proteinebene für Raptor
- p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats
- raptor
- regulatory-associated protein of mTOR
- p150 target of rapamycin (TOR)-scaffold protein
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