RBPJ Produkte
(Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
Kategorien
The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Also, this protein can bind specifically to the recombination signal sequence of immunglobulin kappa type J segments. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2011].
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Ausgewählte RBPJ Kategorien
RBPJ Antikörper
High quality antibodies with extensive validation data.
RBPJ Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RBPJ Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN1538823
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Applikation
WB, IHC, IP
Validierungen
- (5)
Kat. Nr.
ABIN2777213
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN3032451
Menge
0.4 mL
Datenblatt
Datenblatt
Empfohlene RBPJ ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969858
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RBPJ Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317665
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317663
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3095695
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RBPJ Produkten
: "Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells." in: eLife, Vol. 5, (2016) (PubMed).: "A genetic cell context-dependent role for ZEB1 in lung cancer." in: Nature communications, Vol. 7, pp. 12231, (2016) (PubMed).
: "Tumours with elevated levels of the Notch and Wnt pathways exhibit efficacy to PF-03084014, a γ-secretase inhibitor, in a preclinical colorectal explant model." in: British journal of cancer, Vol. 109, Issue 3, pp. 667-75, (2013) (PubMed).
: "RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 41, pp. 13794-807, (2010) (PubMed).
: "A somatic knockout of CBF1 in a human B-cell line reveals that induction of CD21 and CCR7 by EBNA-2 is strictly CBF1 dependent and that downregulation of immunoglobulin M is partially CBF1 ..." in: Journal of virology, Vol. 79, Issue 14, pp. 8784-92, (2005) (PubMed).
Synonyme und alternative Namen zu RBPJ
recombination signal binding protein for immunoglobulin kappa J region (RBPJ), recombination signal binding protein for immunoglobulin kappa J region (Rbpj), recombination signal binding protein for immunoglobulin kappa J region S homeolog (rbpj.S), recombination signal binding protein for immunoglobulin kappa J region a (rbpja), recombination signal binding protein for immunoglobulin kappa J region b (rbpjb), AI843960, AOS3, CBF1, csl, IGKJRB, Igkjrb, IGKJRB1, Igkrsbp, ik:tdsubc_1e8, KBF2, RBP-J, RBP-J kappa, rbpj, RBPJK, RBPjk, RBPSUH, Rbpsuh, rbpsuh, Su(H), Su(H)1, Su(H)2, Su(h)A, su(h)B, SUH, XSu(H), xsu(h)1, xx:tdsubc_1e8Bezeichner auf Proteinebene für RBPJ
- CBF-1
- H-2K binding factor-2
- RBP-J kappa
- RBP-JK
- immunoglobulin kappa J region recombination signal binding protein 1
- recombining binding protein suppressor of hairless
- renal carcinoma antigen NY-REN-30
- suppressor of hairless homolog
- J kappa-recombination signal-binding protein
- X-Su(H)
- suppressor of hairless protein 1
- suppressor of hairless protein homolog
- recombination signal binding protein for immunoglobulin kappa J region a
- tdsubc_1e8
- suppressor of hairless 2
- recombining binding protein suppressor of hairless-like
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