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RCC1 Produkte

(Regulator of Chromosome Condensation 1 (RCC1))

Kategorien

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo- cytoplasmic transport, mitosis and nuclear-envelope assembly.

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Ausgewählte RCC1 Kategorien

RCC1 Antikörper

High quality antibodies with extensive validation data.

RCC1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene RCC1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (13)
Kat. Nr. ABIN6146817
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, IF
Validierungen
  • (5)
Kat. Nr. ABIN7262150
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC (p)
Validierungen
  • (5)
Kat. Nr. ABIN560352
Menge 100 μg
Datenblatt Datenblatt

Empfohlene RCC1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6207329
Menge 96 tests
Datenblatt Datenblatt

Empfohlene RCC1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1317692
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1317690
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2730653
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren RCC1 Produkten

Hayes, Duan, Bowen, Kalab, Rothstein: "C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import." in: eLife, Vol. 9, (2020) (PubMed).

Gillon, Nielsen, Steel, Cornwall, Sheard: "Exercise attenuates age-associated changes in motoneuron number, nucleocytoplasmic transport proteins and neuromuscular health." in: GeroScience, Vol. 40, Issue 2, pp. 177-192, (2018) (PubMed).

Wang, Xue, Hu, Wei, Zhang, Ge, Liang: "Structure-dependent mitochondrial dysfunction and hypoxia induced with single-walled carbon nanotubes." in: Small (Weinheim an der Bergstrasse, Germany), Vol. 10, Issue 14, pp. 2859-69, (2014) (PubMed).

Li, Zheng: "Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells." in: Genes & development, Vol. 18, Issue 5, pp. 512-27, (2004) (PubMed).

Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, (2004) (PubMed).

Cushman, Stenoien, Moore: "The dynamic association of RCC1 with chromatin is modulated by Ran-dependent nuclear transport." in: Molecular biology of the cell, Vol. 15, Issue 1, pp. 245-55, (2003) (PubMed).

Ciarallo, Subramaniam, Hung, Lee, Kotchetkov, Sandhu, Milic, Slingerland: "Altered p27(Kip1) phosphorylation, localization, and function in human epithelial cells resistant to transforming growth factor beta-mediated G(1) arrest." in: Molecular and cellular biology, Vol. 22, Issue 9, pp. 2993-3002, (2002) (PubMed).

Saitoh, Pizzi, Wang: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).

Bilbao-Cortés, Hetzer, Längst, Becker, Mattaj: "Ran binds to chromatin by two distinct mechanisms." in: Current biology : CB, Vol. 12, Issue 13, pp. 1151-6, (2002) (PubMed).

Nemergut, Lindsay, Brownawell, Macara: "Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor." in: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 17385-8, (2002) (PubMed).

Synonyme und alternative Namen zu RCC1

regulator of chromosome condensation 1 (rcc1), regulator of chromosome condensation 1 (RCC1), regulator of chromosome condensation 1 L homeolog (rcc1.L), Regulator of chromosome condensation 1 (Rcc1), N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted (RCC1), regulator of chromosome condensation 1 S homeolog (rcc1.S), regulator of chromosome condensation 1 (Rcc1), 4931417M11Rik, AI326872, BJ1, CG10480, CG18640 (Bj1), Chc1, CHC1, chc1-a, chc1-b, Dmel\\CG10480, dRCC1, inxs, MGC115703, MGC132085, RanGEF, rcc1, RCC1, Rcc1, RCC1-I, sdt, SNHG3-RCC1, wu:fj77f08, xrcc1, zgc:65796, zgc:77114

Bezeichner auf Proteinebene für RCC1

  • chromosome condensation 1
  • fj77f08
  • regulator of chromosome condensation
  • regulator of chromosome condensation 1
  • RCC1 protein
  • Bj1-PA
  • Bj1-PB
  • Bj1-PC
  • CG10480-PA
  • CG10480-PB
  • CG10480-PC
  • in excess
  • side-out
  • possible fragment of potential guanine nucleotide exchange factor
  • SNHG3-RCC1 readthrough transcript
  • cell cycle regulatory protein
  • guanine nucleotide-releasing protein
  • chromosome condensation protein 1
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