RCHY1 Produkte
(Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))
Kategorien
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011].
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Ausgewählte RCHY1 Kategorien
RCHY1 Antikörper
High quality antibodies with extensive validation data.
RCHY1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RCHY1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS, ICC
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN1724723
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7168232
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (2)
Kat. Nr.
ABIN525493
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene RCHY1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6234455
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RCHY1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317698
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317696
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN2131528
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RCHY1 Produkten
: "p27kip1 Expression in non-small cell lung cancer is not an independent prognostic factor." in: Anticancer research, Vol. 30, Issue 9, pp. 3699-704, (2010) (PubMed).: "The Pirh2-keratin 8/18 interaction modulates the cellular distribution of mitochondria and UV-induced apoptosis." in: Cell death and differentiation, Vol. 16, Issue 6, pp. 826-37, (2009) (PubMed).
: "Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domains." in: The Journal of biological chemistry, Vol. 284, Issue 33, pp. 21955-70, (2009) (PubMed).
: "Molecular basis of Pirh2-mediated p53 ubiquitylation." in: Nature structural & molecular biology, Vol. 15, Issue 12, pp. 1334-42, (2008) (PubMed).
: "Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53." in: The EMBO journal, Vol. 26, Issue 13, pp. 3062-74, (2007) (PubMed).
: "Differential response between the p53 ubiquitin-protein ligases Pirh2 and MdM2 following DNA damage in human cancer cells." in: Experimental cell research, Vol. 312, Issue 17, pp. 3370-8, (2006) (PubMed).
: "Activation of p53 in cervical cancer cells by human papillomavirus E6 RNA interference is transient, but can be sustained by inhibiting endogenous nuclear export-dependent p53 antagonists." in: Cancer research, Vol. 66, Issue 24, pp. 11817-24, (2006) (PubMed).
: "Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3." in: The EMBO journal, Vol. 24, Issue 9, pp. 1739-49, (2005) (PubMed).
: "Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer." in: Journal of the National Cancer Institute, Vol. 96, Issue 22, pp. 1718-21, (2004) (PubMed).
Synonyme und alternative Namen zu RCHY1
ring finger and CHY zinc finger domain containing 1 (RCHY1), ring finger and CHY zinc finger domain containing 1 (Rchy1), ring finger and CHY zinc finger domain containing 1 (rchy1), ring finger and CHY zinc finger domain containing 1 L homeolog (rchy1.L), ARNIP, arnip, CHIMP, chimp, harnip, PIRH2, Pirh2, pirh2, PRO1996, pro1996, RCHY1, RNF199, rnf199, wu:fb37e07, Zfp363, zgc:101128, ZNF363, Znf363, znf363Bezeichner auf Proteinebene für RCHY1
- CH-rich interacting match with PLAG1
- E3 ubiquitin-protein ligase Pirh2
- RING finger and CHY zinc finger domain-containing protein 1
- RING finger protein 199
- androgen-receptor N-terminal-interacting protein
- p53-induced protein with a RING-H2 domain
- zinc finger protein 363
- CH-rich-interacting match with PLAG1
- androgen receptor N-terminal-interacting protein
- ring finger and CHY zinc finger domain containing 1
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