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RELB Produkte

(V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))

Kategorien

NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF- kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric RelB-p50 and RelB-p52 complexes are transcriptional activators. Stimulates promoter activity in the presence of p49- and p50-NF-kappa-B. Neither associates with DNA nor with p65-NF-kappa-B (By similarity).

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Ausgewählte RELB Kategorien

RELB Antikörper

High quality antibodies with extensive validation data.

RELB ELISA Kits

Reliable ELISA kits for a wide range of species.

RELB Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene RELB Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, PLA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN519730
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN948396
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IP, IHC (p), ChIP
Validierungen
  • (5)
Kat. Nr. ABIN2855360
Menge 100 μL
Datenblatt Datenblatt

Empfohlene RELB ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6971106
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6960423
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative DNA-Binding ELISA
Validierungen
  • (2)
Kat. Nr. ABIN5690758
Menge 96 tests
Datenblatt Datenblatt

Empfohlene RELB Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1317787
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7394939
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7405328
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren RELB Produkten

Ta, Schwensen, Liuwantara, Huso, Watnick, Rangan: "Constitutive renal Rel/nuclear factor-κB expression in Lewis polycystic kidney disease rats." in: World journal of nephrology, Vol. 5, Issue 4, pp. 339-57, (2016) (PubMed).

Pyz, Naidenko, Miyake, Yamamura, Berberich, Cardell, Kronenberg, Herrmann: "The complementarity determining region 2 of BV8S2 (V beta 8.2) contributes to antigen recognition by rat invariant NKT cell TCR." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 12, pp. 7447-55, (2006) (PubMed).

Kaetzel: "The polymeric immunoglobulin receptor: bridging innate and adaptive immune responses at mucosal surfaces." in: Immunological reviews, Vol. 206, pp. 83-99, (2005) (PubMed).

Marienfeld, Berberich-Siebelt, Berberich, Denk, Serfling, Neumann: "Signal-specific and phosphorylation-dependent RelB degradation: a potential mechanism of NF-kappaB control." in: Oncogene, Vol. 20, Issue 56, pp. 8142-7, (2002) (PubMed).

Synonyme und alternative Namen zu RELB

avian reticuloendotheliosis viral (v-rel) oncogene related B (Relb), RELB proto-oncogene, NF-kB subunit (RELB), RELB proto-oncogene, NF-kB subunit (Relb), v-rel avian reticuloendotheliosis viral oncogene homolog B S homeolog (relb.S), GC-rich, I-REL, IREL, REL-B, relb-A, shep, XRelB

Bezeichner auf Proteinebene für RELB

  • transcription factor RelB
  • v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
  • v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
  • avian reticuloendotheliosis viral (v-rel) oncogene related B
  • v-rel reticuloendotheliosis viral oncogene homolog B
  • transcription factor RelB homolog
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