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Retinal Pigment Epithelium-Specific Protein 65kDa Produkte

(Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))
This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa. [provided by RefSeq, Jul 2008].

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Ausgewählte Retinal Pigment Epithelium-Specific Protein 65kDa Kategorien

Retinal Pigment Epithelium-Specific Protein 65kDa Antikörper

High quality antibodies with extensive validation data.

Retinal Pigment Epithelium-Specific Protein 65kDa ELISA Kits

Reliable ELISA kits for a wide range of species.

Retinal Pigment Epithelium-Specific Protein 65kDa Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Retinal Pigment Epithelium-Specific Protein 65kDa Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, IHC
Validierungen
  • (5)
Kat. Nr. ABIN7269933
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (3)
Kat. Nr. ABIN7167824
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (3)
Kat. Nr. ABIN6147090
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Retinal Pigment Epithelium-Specific Protein 65kDa ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6221142
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6221145
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5593944
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Retinal Pigment Epithelium-Specific Protein 65kDa Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7422823
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7422820
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2731119
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Retinal Pigment Epithelium-Specific Protein 65kDa Produkten

Tichotová, Studenovska, Petrovski, Popelka, Nemesh, Sedláčková, Drutovič, Rohiwal, Jendelová, Erceg, Brymová, Artero-Castro, Lytvynchuk, Straňák, Ellederová, Motlík, Ardan: "Advantages of nanofibrous membranes for culturing of primary RPE cells compared to commercial scaffolds." in: Acta ophthalmologica, (2021) (PubMed).

Cho, Park, Lee, Nah, Park, Yang, Madrakhimov, Lyu, Park: "The role of Wnt/β-catenin signaling in the restoration of induced pluripotent stem cell-derived retinal pigment epithelium after laser photocoagulation." in: Lasers in medical science, Vol. 34, Issue 3, pp. 571-581, (2019) (PubMed).

Cai, Gong, Abriola, Hoyer, Nyscf Global Stem Cell Array Team, Noggle, Paull, Del Priore, Fields: "High-throughput screening identifies compounds that protect RPE cells from physiological stressors present in AMD." in: Experimental eye research, Vol. 185, pp. 107641, (2019) (PubMed).

Gao, Liao, Chen, Liao, He, Chen, Ma, Liu, Wu: "Conversion of all-trans-retinal into all-trans-retinal dimer reflects an alternative metabolic/antidotal pathway of all-trans-retinal in the retina." in: The Journal of biological chemistry, Vol. 293, Issue 37, pp. 14507-14519, (2019) (PubMed).

Scruggs, Jiao, Cranston, Kaalberg, Wang, Russell, Wiley, Mullins, Stone, Tucker, Sohn: "Optimizing Donor Cellular Dissociation and Subretinal Injection Parameters for Stem Cell-Based Treatments." in: Stem cells translational medicine, Vol. 8, Issue 8, pp. 797-809, (2019) (PubMed).

Wright, Brisson, Wood, Oblak, Mutsaers, Sabine, Skowronski, Belanger, Tiessen, Bienzle: "Flow Cytometric Detection of Circulating Osteosarcoma Cells in Dogs." in: Cytometry. Part A : the journal of the International Society for Analytical Cytology, (2019) (PubMed).

Sun, Huang, Liang, Li, Shen, She, Feng, Luo, Liu, Sun: "Cooperation of Rel family members in regulating Aβ1-40-mediated pro-inflammatory cytokine secretion by retinal pigment epithelial cells." in: Cell death & disease, Vol. 8, Issue 10, pp. e3115, (2018) (PubMed).

Bhutto, Ogura, Baldeosingh, McLeod, Lutty, Edwards: "An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy." in: Investigative ophthalmology & visual science, Vol. 59, Issue 4, pp. AMD143-AMD151, (2018) (PubMed).

Llonch, Carido, Ader: "Organoid technology for retinal repair." in: Developmental biology, Vol. 433, Issue 2, pp. 132-143, (2018) (PubMed).

Kaur, Tan, Rathnasamy, La Cunza, Germer, Toops, Fernandes, Blenkinsop, Lakkaraju: "Aberrant early endosome biogenesis mediates complement activation in the retinal pigment epithelium in models of macular degeneration." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 36, pp. 9014-9019, (2018) (PubMed).

Synonyme und alternative Namen zu Retinal Pigment Epithelium-Specific Protein 65kDa

RPE65, retinoid isomerohydrolase (RPE65), retinal pigment epithelium 65 (Rpe65), neither inactivation nor afterpotential B (ninaB), RPE65, retinoid isomerohydrolase (Rpe65), retinal pigment epithelium-specific protein 65kDa S homeolog (rpe65.S), retinal pigment epithelium-specific protein 65kDa L homeolog (rpe65.L), RPE65 homolog (rpe65), retinal pigment epithelium-specific protein 65kDa (rpe65), retinal pigment epithelium-specific protein 65c (rpe65c), retinal pigment epithelium-specific protein 65b (rpe65b), retinal pigment epithelium-specific protein 65a (rpe65a), 13cIMH, 65kDa, A930029L06Rik, anon-WO0148162.1, anon-WO0148163.1, beta-diox, CG9347, DmelCG9347, DRPE65, LCA2, MGC52887, MGC85437, MGC154296, Mord1, mRPE65, rd12, RP20, RPE56a, RPE56b, RPE56c, RPE65, rpe65, rpepa, rpepb, si:ch211-198n5.5, si:ch211-198n5.12, sRPE65, wu:fc74c09, zgc:73213, zgc:110538

Bezeichner auf Proteinebene für Retinal Pigment Epithelium-Specific Protein 65kDa

  • RBP-binding membrane protein
  • all-trans-retinyl-palmitate hydrolase
  • p63
  • retinal pigment epithelium-specific 65 kDa protein
  • retinitis pigmentosa 20 (autosomal recessive)
  • retinoid isomerohydrolase
  • retinol isomerase
  • modifier of retinal degeneration 1
  • retinal pigment epithelium, 65 kDa
  • neither inactivation nor afterpotential B
  • CG9347-PA
  • ninaB-PA
  • beta-carotene dioxygenase
  • retinal pigment epithelium 65-like
  • retinal pigment epithelium-specific protein (65kD)
  • retinal pigment epithelium-specific protein 65kDa
  • retinal pigment epithelium abundant protein RPE65
  • rpe65 gene for retinal pigment epithelium-specific protein
  • RPE65 homolog
  • retinoid isomerohydrolase-like
  • All-trans-retinyl ester 13-cis isomerohydrolase C
  • All-trans-retinylester 11-cis isomerohydrolase C
  • Retinal pigment epithelium-specific 65 kDa protein homolog C
  • retinal Mueller cells isomerohydrolase
  • 13cIMH
  • Retinal pigment epithelium-specific 65 kDa protein homolog B
  • all-trans-retinyl ester 13-cis isomerohydrolase
  • retinal pigment epithelium 65b
  • retinal pigment epithelium-specific 65 kDa protein homolog B
  • retinal pigment epithelium-specific protein b
  • All-trans-retinylester 11-cis isomerohydrolase A
  • Retinal pigment epithelium-specific 65 kDa protein homolog A
  • all-trans-retinylester 11-cis isomerohydrolase A
  • retinal pigment epithelium 65a
  • retinal pigment epithelium-specific 65 kDa protein homolog A
  • retinal pigment epithelium-specific protein a
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