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Retinoblastoma Binding Protein 8 Produkte

(Retinoblastoma Binding Protein 8 (RBBP8))

Kategorien

The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008].

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Ausgewählte Retinoblastoma Binding Protein 8 Kategorien

Retinoblastoma Binding Protein 8 Antikörper

High quality antibodies with extensive validation data.

Retinoblastoma Binding Protein 8 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Retinoblastoma Binding Protein 8 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN604928
Menge 50 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7150164
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN2856639
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Retinoblastoma Binding Protein 8 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6203591
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Retinoblastoma Binding Protein 8 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1317559
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3091883
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3136083
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Retinoblastoma Binding Protein 8 Produkten

Chen, Chen, Qiao, Shi, Liu, Zeng, Xie, Shi, Sun, Liu, Li, Zhou, Wan, Xie, Wang, Wang: "ZNF830 mediates cancer chemoresistance through promoting homologous-recombination repair." in: Nucleic acids research, Vol. 46, Issue 3, pp. 1266-1279, (2018) (PubMed).

Lee, Im, Shibata, Dutta: "ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks." in: Molecular cell, Vol. 68, Issue 1, pp. 61-75.e5, (2017) (PubMed).

Onyango, Howard, Neherin, Yanez, Stark: "Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination." in: Nucleic acids research, Vol. 44, Issue 12, pp. 5702-16, (2016) (PubMed).

Bakr, Köcher, Volquardsen, Petersen, Borgmann, Dikomey, Rothkamm, Mansour: "Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1." in: Oncotarget, Vol. 7, Issue 36, pp. 57679-57693, (2016) (PubMed).

Kuo, Li, Stark, Shih, Ann: "RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 6, pp. 787-98, (2016) (PubMed).

Lee, Im, Shibata, Park, Handa, Kowalczykowski, Dutta: "MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex." in: Nature communications, Vol. 6, pp. 7744, (2015) (PubMed).

Unno, Itaya, Taoka, Sato, Tomida, Sakai, Sugasawa, Ishiai, Ikura, Isobe, Kurumizaka, Takata: "FANCD2 binds CtIP and regulates DNA-end resection during DNA interstrand crosslink repair." in: Cell reports, Vol. 7, Issue 4, pp. 1039-47, (2014) (PubMed).

Zhou, Caron, Legube, Paull: "Quantitation of DNA double-strand break resection intermediates in human cells." in: Nucleic acids research, Vol. 42, Issue 3, pp. e19, (2014) (PubMed).

Makharashvili, Tubbs, Yang, Wang, Barton, Zhou, Deshpande, Lee, Lobrich, Sleckman, Wu, Paull: "Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection." in: Molecular cell, Vol. 54, Issue 6, pp. 1022-33, (2014) (PubMed).

Yin, Seifert, Chua, Maure, Golebiowski, Hay: "SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage." in: Genes & development, Vol. 26, Issue 11, pp. 1196-208, (2012) (PubMed).

Synonyme und alternative Namen zu Retinoblastoma Binding Protein 8

RB binding protein 8, endonuclease (RBBP8), retinoblastoma binding protein 8, endonuclease (Rbbp8), RB binding protein 8, endonuclease (Rbbp8), retinoblastoma binding protein 8 L homeolog (rbbp8.L), retinoblastoma binding protein 8 (rbbp8), 9930104E21Rik, COM1, CTIP, CtIP, DKFZp469K0714, JWDS, RBBP-8, RBBP8, RGD1308872, RIM, SAE2, SCKL2

Bezeichner auf Proteinebene für Retinoblastoma Binding Protein 8

  • CTBP-interacting protein
  • DNA endonuclease RBBP8
  • RBBP-8
  • sporulation in the absence of SPO11 protein 2 homolog
  • ctBP-interacting protein
  • retinoblastoma-binding protein 8
  • retinoblastoma binding protein 8
  • CtBP-interacting protein
  • retinoblastoma-binding protein 8-like
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