Ring Finger Protein 8 Produkte
(Ring Finger Protein 8 (RNF8))
Kategorien
The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].
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Ausgewählte Ring Finger Protein 8 Kategorien
Ring Finger Protein 8 Antikörper
High quality antibodies with extensive validation data.
Ring Finger Protein 8 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Ring Finger Protein 8 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (4)
- (3)
Kat. Nr.
ABIN522468
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, FACS
Validierungen
- (4)
Kat. Nr.
ABIN184931
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cow, Human, Mouse, Rat, Xenopus laevis
Applikation
WB, IHC
Validierungen
- (3)
Kat. Nr.
ABIN925946
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene Ring Finger Protein 8 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6207377
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Ring Finger Protein 8 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN1318397
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3095050
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3136693
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Ring Finger Protein 8 Produkten
: "RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9396-410, (2016) (PubMed).: "Epstein-Barr virus BZLF1 protein impairs accumulation of host DNA damage proteins at damage sites in response to DNA damage." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 8, pp. 937-50, (2015) (PubMed).
: "Role of ATM in the formation of the replication compartment during lytic replication of Epstein-Barr virus in nasopharyngeal epithelial cells." in: Journal of virology, Vol. 89, Issue 1, pp. 652-68, (2014) (PubMed).
: "Solubility-based genetic screen identifies RING finger protein 126 as an E3 ligase for activation-induced cytidine deaminase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 3, pp. 1029-34, (2013) (PubMed).
: "Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage." in: The Journal of biological chemistry, Vol. 288, Issue 5, pp. 2941-50, (2013) (PubMed).
: "Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1." in: Nature, Vol. 466, Issue 7309, pp. 941-6, (2010) (PubMed).
: "The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress." in: Nature, Vol. 462, Issue 7275, pp. 886-90, (2009) (PubMed).
: "N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8." in: European journal of biochemistry / FEBS, Vol. 268, Issue 9, pp. 2725-32, (2001) (PubMed).
Synonyme und alternative Namen zu Ring Finger Protein 8
ring finger protein 8 (RNF8), ring finger protein 8 (Rnf8), ring finger protein 8, E3 ubiquitin protein ligase S homeolog (rnf8.S), ring finger protein 8, E3 ubiquitin protein ligase L homeolog (rnf8.L), ring finger protein 8, E3 ubiquitin protein ligase (rnf8), 3830404E21Rik, AIP37, fc66f09, hRNF8, RNF8, rnf8, wu:fc66f09, zgc:55936, zgc:77313Bezeichner auf Proteinebene für Ring Finger Protein 8
- C3HC4-type zinc finger protein
- E3 ubiquitin-protein ligase RNF8
- UBC13/UEV-interacting ring finger protein
- ring finger protein (C3HC4 type) 8
- ActA binding protein 2
- actA-interacting protein 37
- laXp180
- E3 ubiquitin-protein ligase RNF8 A
- E3 ubiquitin-protein ligase RNF8-A
- RING finger protein 8 A
- RING finger protein 8-A
- E3 ubiquitin-protein ligase RNF8 B
- E3 ubiquitin-protein ligase RNF8-B
- RING finger protein 8 B
- RING finger protein 8-B
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