RNF111 Produkte
(Ring Finger Protein 111 (RNF111))
Kategorien
The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012].
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Ausgewählte RNF111 Kategorien
RNF111 Antikörper
High quality antibodies with extensive validation data.
RNF111 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RNF111 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, RNAi
Validierungen
- (9)
- (5)
Kat. Nr.
ABIN527194
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
- (3)
Kat. Nr.
ABIN527193
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF, ICC
Validierungen
- (2)
Kat. Nr.
ABIN6257485
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene RNF111 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1318194
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3095070
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3136968
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RNF111 Produkten
: "The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma." in: Oncogene, Vol. 35, Issue 27, pp. 3514-23, (2016) (PubMed).: "SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair." in: Nature communications, Vol. 6, pp. 7499, (2015) (PubMed).
: "Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-? signalling." in: Nature communications, Vol. 5, pp. 3388, (2014) (PubMed).
: "Multiple Arkadia/RNF111 structures coordinate its Polycomb body association and transcriptional control." in: Molecular and cellular biology, Vol. 34, Issue 16, pp. 2981-95, (2014) (PubMed).
: "RNF111-dependent neddylation activates DNA damage-induced ubiquitination." in: Molecular cell, Vol. 49, Issue 5, pp. 897-907, (2013) (PubMed).
: "Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation." in: Molecular and cellular biology, Vol. 33, Issue 11, pp. 2163-77, (2013) (PubMed).
: "RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response." in: The Journal of cell biology, Vol. 201, Issue 6, pp. 797-807, (2013) (PubMed).
: "Efficient TGF-?/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression." in: Molecular cancer, Vol. 10, Issue 1, pp. 2, (2011) (PubMed).
: "RB1CC1 protein positively regulates transforming growth factor-beta signaling through the modulation of Arkadia E3 ubiquitin ligase activity." in: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32502-12, (2011) (PubMed).
: "Context-dependent regulation of the expression of c-Ski protein by Arkadia in human cancer cells." in: Journal of biochemistry, Vol. 147, Issue 4, pp. 545-54, (2010) (PubMed).
Synonyme und alternative Namen zu RNF111
ring finger protein 111 (RNF111), ring finger 111 (Rnf111), ring finger protein 111 (Rnf111), ring finger protein 111 (rnf111-b), ring finger protein 111 (rnf111), ARK, ark, Arkadia, MGC81253, MGC146379, RNF111, rnf111Bezeichner auf Proteinebene für RNF111
- Arkadia
- E3 ubiquitin-protein ligase Arkadia
- RING finger protein 111
- ring finger 111
- arkadia
- ring finger protein 111
- E3 ubiquitin-protein ligase arkadia-B
- RING finger protein 111-B
- e3 ubiquitin-protein ligase Arkadia-like
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