RNF20 Produkte
(Ring Finger Protein 20 (RNF20))
Kategorien
The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012].
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Ausgewählte RNF20 Kategorien
RNF20 Antikörper
High quality antibodies with extensive validation data.
RNF20 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RNF20 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (4)
Kat. Nr.
ABIN1327712
Menge
50 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IF, ICC
Validierungen
- (2)
Kat. Nr.
ABIN6264788
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN4913698
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene RNF20 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6207367
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RNF20 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1318333
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3090157
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3135178
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RNF20 Produkten
: "Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy." in: Nucleic acids research, Vol. 45, Issue 3, pp. 1144-1158, (2017) (PubMed).: "Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy." in: Nucleic acids research, (2016) (PubMed).
: "Microarray Analysis Reveals Potential Biological Functions of Histone H2B Monoubiquitination." in: PLoS ONE, Vol. 10, Issue 7, pp. e0133444, (2015) (PubMed).
: "Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 10, pp. 3901-6, (2013) (PubMed).
: "The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2)." in: The Journal of biological chemistry, Vol. 288, Issue 33, pp. 24234-46, (2013) (PubMed).
: "The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination." in: Human molecular genetics, Vol. 21, Issue 3, pp. 559-68, (2012) (PubMed).
: "Histone H2B ubiquitin ligases RNF20 and RNF40 in androgen signaling and prostate cancer cell growth." in: Molecular and cellular endocrinology, Vol. 350, Issue 1, pp. 87-98, (2012) (PubMed).
: "Promoters active in interphase are bookmarked during mitosis by ubiquitination." in: Nucleic acids research, Vol. 40, Issue 20, pp. 10187-202, (2012) (PubMed).
: "Nucleosomal H2B ubiquitylation with purified factors." in: Methods (San Diego, Calif.), Vol. 54, Issue 3, pp. 331-8, (2011) (PubMed).
: "A member of the ETS family, EHF, and the ATPase RUVBL1 inhibit p53-mediated apoptosis." in: EMBO reports, Vol. 12, Issue 7, pp. 682-9, (2011) (PubMed).
Synonyme und alternative Namen zu RNF20
ring finger protein 20 (RNF20), ring finger protein 20 (Rnf20), 4833430L21Rik, AW540162, BRE1, BRE1A, C79397, hBRE1, mKIAA4116Bezeichner auf Proteinebene für RNF20
- BRE1-A
- E3 ubiquitin-protein ligase BRE1A
- BRE1 E3 ubiquitin ligase homolog
- homolog of S. cerevisiae BRE1
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