RPA1 Produkte
(Replication Protein A1, 70kDa (RPA1))
Kategorien
Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair\; it does not support chromosomal DNA replication and cell cycle progression through S- phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.
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Ausgewählte RPA1 Kategorien
RPA1 Antikörper
High quality antibodies with extensive validation data.
RPA1 ELISA Kits
Reliable ELISA kits for a wide range of species.
RPA1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RPA1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS, ICC
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN969564
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IP, IHC (p), ICC
Validierungen
- (7)
Kat. Nr.
ABIN2856633
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF, FACS
Validierungen
- (7)
Kat. Nr.
ABIN1500741
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene RPA1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959123
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959124
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4972520
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RPA1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124825
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1318500
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7408951
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RPA1 Produkten
: "The nuclear DEK interactome supports multi-functionality." in: Proteins, Vol. 86, Issue 1, pp. 88-97, (2018) (PubMed).: "ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress." in: Cell, Vol. 158, Issue 3, pp. 633-46, (2014) (PubMed).
: "RPA coordinates DNA end resection and prevents formation of DNA hairpins." in: Molecular cell, Vol. 50, Issue 4, pp. 589-600, (2013) (PubMed).
: "MRX protects fork integrity at protein-DNA barriers, and its absence causes checkpoint activation dependent on chromatin context." in: Nucleic acids research, Vol. 41, Issue 5, pp. 3173-89, (2013) (PubMed).
: "Phenothiazine Inhibitors of TLKs Affect Double-Strand Break Repair and DNA Damage Response Recovery and Potentiate Tumor Killing with Radiomimetic Therapy." in: Genes & cancer, Vol. 4, Issue 1-2, pp. 39-53, (2013) (PubMed).
: "Mechanism of release and fate of excised oligonucleotides during nucleotide excision repair." in: The Journal of biological chemistry, Vol. 287, Issue 27, pp. 22889-99, (2012) (PubMed).
: "In vitro analysis of the role of replication protein A (RPA) and RPA phosphorylation in ATR-mediated checkpoint signaling." in: The Journal of biological chemistry, Vol. 287, Issue 43, pp. 36123-31, (2012) (PubMed).
: "The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19237-46, (2011) (PubMed).
: "Role of interaction of XPF with RPA in nucleotide excision repair." in: Journal of molecular biology, Vol. 413, Issue 2, pp. 337-46, (2011) (PubMed).
: "Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation." in: Molecular and cellular biology, Vol. 30, Issue 6, pp. 1382-96, (2010) (PubMed).
Synonyme und alternative Namen zu RPA1
replication protein A1 (RPA1), replication protein A1 (Rpa1), replication protein A1 (rpa1), replication protein A1, 70kDa (RPA1), replication protein A1 L homeolog (rpa1.L), Replication Protein A 70 (RpA-70), 70kDa, 5031405K23Rik, AA589576, AW557552, Cb1-727, CG9633, D-RPA70, D-SSB, Dmel\\CG9633, DmRPA, dmrpa1, DRP-A, dRP-A, HSSB, hssb, i164, LOC100230990, MST075, mst075, REPA1, repa1, RF-A, rf-a, RP-A, rp-a, rpa, Rpa, RPA, Rpa-70, RPA1, RPA70, rpa70, RPA 70, RpA70, RPA 70 kDa, Ssb-70, wu:fi14b08, zgc:55337, zgc:77092Bezeichner auf Proteinebene für RPA1
- MSTP075
- RF-A protein 1
- RP-A p70
- replication factor A protein 1
- replication protein A 70 kDa DNA-binding subunit
- single-stranded DNA-binding protein
- replication protein A1, 70kDa
- replication protein A1
- replication protein A 70 kDa DNA-binding subunit-like
- replication protein A (RPA)
- CG9633-PA
- RpA-70-PA
- drosophila replication protein A
- replication protein A 70
- single stranded-binding protein 70
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