RRM1 Produkte
(Ribonucleotide Reductase M1 (RRM1))
Kategorien
This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq, Jul 2008].
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Ausgewählte RRM1 Kategorien
RRM1 Antikörper
High quality antibodies with extensive validation data.
RRM1 ELISA Kits
Reliable ELISA kits for a wide range of species.
RRM1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RRM1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS
Validierungen
- (7)
Kat. Nr.
ABIN7193575
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF, IP
Validierungen
- (7)
Kat. Nr.
ABIN3021563
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7436186
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene RRM1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969958
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959185
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959186
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RRM1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1318900
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1318898
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7408315
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RRM1 Produkten
: "Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 107, (2018) (PubMed).: "Bcl2 induces DNA replication stress by inhibiting ribonucleotide reductase." in: Cancer research, Vol. 74, Issue 1, pp. 212-23, (2014) (PubMed).
: "The effect of the acid-sensitivity of 4-(N)-stearoyl gemcitabine-loaded micelles on drug resistance caused by RRM1 overexpression." in: Biomaterials, Vol. 34, Issue 9, pp. 2327-39, (2013) (PubMed).
: "Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 157, Issue 1, pp. 132-40, (2012) (PubMed).
: "Silencing of ribonucleotide reductase subunit M1 potentiates the antitumor activity of gemcitabine in resistant cancer cells." in: Cancer biology & therapy, Vol. 13, Issue 10, pp. 908-14, (2012) (PubMed).
: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." in: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
Synonyme und alternative Namen zu RRM1
ribonucleotide reductase catalytic subunit M1 (RRM1), Ribonucleoside diphosphate reductase large subunit (RnrL), ribonucleoside-diphosphate reductase large subunit (LOC100472317), ribonucleotide reductase catalytic subunit M1 (rrm1), ribonucleotide reductase M1 L homeolog (rrm1.L), ribonucleotide reductase M1 (Rrm1), ribonucleotide reductase catalytic subunit M1 (Rrm1), ribonucleotide reductase M1 (RRM1), ribonucleotide reductase M1 polypeptide (rrm1), cb396, cb838, CG5371, CHUNP6866, Dmel\\CG5371, DmRNR1, l(2)k06709, R1, r1, RIR1, RNR1, RnrM1, RntL, RR1, sb:cb548, wu:fb39b07, wu:fi14b02, wu:fk95f07, XRRM1Bezeichner auf Proteinebene für RRM1
- ribonucleoside diphosphate reductase large subunit
- CG5371-PA
- RnrL-PA
- ribonucleoside diphosphate reductase M1 subunit
- ribonucleoside-diphosphate reductase large subunit
- ribonucleoside-diphosphate reductase M1 chain
- ribonucleotide reductase M1 polypeptide
- ribonucleotide reductase M1
- ribonucleoside-diphosphate reductase large subunit-like
- ribonucleoside-diphosphate reductase subunit M1
- ribonucleotide reductase, R1 subunit
- ribonucleotide reductase large subunit
- ribonucleotide reductase protein r1 class I
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