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RRM1 Produkte

(Ribonucleotide Reductase M1 (RRM1))
This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq, Jul 2008].

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Ausgewählte RRM1 Kategorien

RRM1 Antikörper

High quality antibodies with extensive validation data.

RRM1 ELISA Kits

Reliable ELISA kits for a wide range of species.

RRM1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene RRM1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS
Validierungen
  • (7)
Kat. Nr. ABIN7193575
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF, IP
Validierungen
  • (7)
Kat. Nr. ABIN3021563
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7436186
Menge 100 μL
Datenblatt Datenblatt

Empfohlene RRM1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969958
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959185
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959186
Menge 96 tests
Datenblatt Datenblatt

Empfohlene RRM1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1318900
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1318898
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7408315
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren RRM1 Produkten

Xia, Wang, Song, Meng, Huang, Huang: "Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 107, (2018) (PubMed).

Xie, Yen, Owonikoko, Ramalingam, Khuri, Curran, Doetsch, Deng: "Bcl2 induces DNA replication stress by inhibiting ribonucleotide reductase." in: Cancer research, Vol. 74, Issue 1, pp. 212-23, (2014) (PubMed).

Zhu, Wonganan, Lansakara-P, OMary, Li, Cui: "The effect of the acid-sensitivity of 4-(N)-stearoyl gemcitabine-loaded micelles on drug resistance caused by RRM1 overexpression." in: Biomaterials, Vol. 34, Issue 9, pp. 2327-39, (2013) (PubMed).

Chung, Sandoval, Sloat, Lansakara-P, Cui: "Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 157, Issue 1, pp. 132-40, (2012) (PubMed).

Wonganan, Chung, Zhu, Kiguchi, Digiovanni, Cui: "Silencing of ribonucleotide reductase subunit M1 potentiates the antitumor activity of gemcitabine in resistant cancer cells." in: Cancer biology & therapy, Vol. 13, Issue 10, pp. 908-14, (2012) (PubMed).

Ucisik-Akkaya, Davis, Do, Morrison, Stemmer, Amadio, Dorak: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." in: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, (2010) (PubMed).

Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).

Synonyme und alternative Namen zu RRM1

ribonucleotide reductase catalytic subunit M1 (RRM1), Ribonucleoside diphosphate reductase large subunit (RnrL), ribonucleoside-diphosphate reductase large subunit (LOC100472317), ribonucleotide reductase catalytic subunit M1 (rrm1), ribonucleotide reductase M1 L homeolog (rrm1.L), ribonucleotide reductase M1 (Rrm1), ribonucleotide reductase catalytic subunit M1 (Rrm1), ribonucleotide reductase M1 (RRM1), ribonucleotide reductase M1 polypeptide (rrm1), cb396, cb838, CG5371, CHUNP6866, Dmel\\CG5371, DmRNR1, l(2)k06709, R1, r1, RIR1, RNR1, RnrM1, RntL, RR1, sb:cb548, wu:fb39b07, wu:fi14b02, wu:fk95f07, XRRM1

Bezeichner auf Proteinebene für RRM1

  • ribonucleoside diphosphate reductase large subunit
  • CG5371-PA
  • RnrL-PA
  • ribonucleoside diphosphate reductase M1 subunit
  • ribonucleoside-diphosphate reductase large subunit
  • ribonucleoside-diphosphate reductase M1 chain
  • ribonucleotide reductase M1 polypeptide
  • ribonucleotide reductase M1
  • ribonucleoside-diphosphate reductase large subunit-like
  • ribonucleoside-diphosphate reductase subunit M1
  • ribonucleotide reductase, R1 subunit
  • ribonucleotide reductase large subunit
  • ribonucleotide reductase protein r1 class I
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