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RUNX1 Produkte

(Runt-Related Transcription Factor 1 (RUNX1))
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte RUNX1 Kategorien

RUNX1 Antikörper

High quality antibodies with extensive validation data.

RUNX1 ELISA Kits

Reliable ELISA kits for a wide range of species.

RUNX1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene RUNX1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC (p)
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN514054
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (9)
Kat. Nr. ABIN6147309
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (6)
Kat. Nr. ABIN3022804
Menge 100 μL
Datenblatt Datenblatt

Empfohlene RUNX1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Analytical Method Qualitative DNA-Binding ELISA
Validierungen
Kat. Nr. ABIN5648548
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validierungen
Kat. Nr. ABIN5648547
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380825
Menge 2 x 96 tests
Datenblatt Datenblatt

Empfohlene RUNX1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN2731253
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1318992
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7420045
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren RUNX1 Produkten

Hong, He, Li, Chu, Pu, Tong, Joshi, Tang, Li: "Runt-related transcription factor 1 promotes apoptosis and inhibits neuroblastoma progression in vitro and in vivo." in: Journal of experimental & clinical cancer research : CR, Vol. 39, Issue 1, pp. 52, (2020) (PubMed).

Illendula, Gilmour, Grembecka, Tirumala, Boulton, Kuntimaddi, Schmidt, Wang, Pulikkan, Zong, Parlak, Kuscu, Pickin, Zhou, Gao, Mishra, Adli, Castilla, Rajewski, Janes, Guzman, Bonifer, Bushweller: "Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers." in: EBioMedicine, Vol. 8, pp. 117-31, (2016) (PubMed).

Miao, Zhao, Zhao, Wang, Liu, Ma, Xue: "MiR-18a increased the permeability of BTB via RUNX1 mediated down-regulation of ZO-1, occludin and claudin-5." in: Cellular signalling, Vol. 27, Issue 1, pp. 156-67, (2015) (PubMed).

Dobson, Taipaleenmäki, Hu, Hong, van Wijnen, Stein, Stein, Lian, Pratap: "hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3." in: Cancer cell international, Vol. 14, pp. 73, (2014) (PubMed).

Ferrari, Mohammed, Nixon, Mason, Mallon, McMillan, Morris, Cameron, Edwards, Blyth: "Expression of RUNX1 correlates with poor patient prognosis in triple negative breast cancer." in: PLoS ONE, Vol. 9, Issue 6, pp. e100759, (2014) (PubMed).

Mochin, Underwood, Cooper, McLenithan, Pierce, Nalvarte, Arbiser, Karlsson, Moise, Moskovitz, Passaniti: "Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells." in: Microvascular research, Vol. 97, pp. 55-64, (2014) (PubMed).

Du, Li, Zhong, Fan, Qiao, He, Fu, Wang, Ye: "Brain death induces the alteration of liver protein expression profiles in rabbits." in: International journal of molecular medicine, Vol. 34, Issue 2, pp. 578-84, (2014) (PubMed).

Keita, Bachvarova, Morin, Plante, Gregoire, Renaud, Sebastianelli, Trinh, Bachvarov: "The RUNX1 transcription factor is expressed in serous epithelial ovarian carcinoma and contributes to cell proliferation, migration and invasion." in: Cell cycle (Georgetown, Tex.), Vol. 12, Issue 6, pp. 972-86, (2013) (PubMed).

Niu, Kondo, Nakazawa, Oishi, Kawasaki, Mochizuki, Yamane, Katoh: "Transcription factor Runx2 is a regulator of epithelial-mesenchymal transition and invasion in thyroid carcinomas." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 92, Issue 8, pp. 1181-90, (2012) (PubMed).

Taniuchi, Osato, Ito: "Runx1: no longer just for leukemia." in: The EMBO journal, Vol. 31, Issue 21, pp. 4098-9, (2012) (PubMed).

Synonyme und alternative Namen zu RUNX1

uncharacterized LOC473981 (LOC473981), runt-related transcription factor (runt), runt related transcription factor 1 (Runx1), runt related transcription factor 1 (RUNX1), runt-related transcription factor 1 (runx1), runt related transcription factor 1 L homeolog (runx1.L), runt-related transcription factor 1 (RUNX1), runt-related transcription factor 1 (Runx1), AI462102, aml, aml-1, AML1, aml1, Aml1, AML1-EVI-1, aml1-evi-1, AMLCR1, amlcr1, Cbfa2, CBFA2, cbfa2, EVI-1, evi-1, Pebp2a2, PEBP2aB, pebp2ab, Pebpa2b, Runx-1, RUNX1, runx1, runxa, XAML, Xaml1

Bezeichner auf Proteinebene für RUNX1

  • runt-related transcription factor 1
  • runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)
  • runt-related transcription factor
  • runt protein
  • CBF-alpha-2
  • PEA2-alpha B
  • PEBP2-alpha B
  • SL3-3 enhancer factor 1 alpha B subunit
  • SL3/AKV core-binding factor alpha B subunit
  • acute myeloid leukemia 1 protein
  • core binding factor alpha 2
  • core-binding factor subunit alpha-2
  • oncogene AML-1
  • polyomavirus enhancer-binding protein 2 alpha B subunit
  • runt domain, alpha subunit 2
  • AML1-EVI-1 fusion protein
  • core-binding factor, runt domain, alpha subunit 2
  • aml1
  • runt-related transcription factor a
  • runx1a
  • Acute myeloid leukemia 1 protein
  • Core-binding factor subunit alpha-2
  • aml1 oncogene
  • ch-runtB2
  • acute myeloid leukemia 1
  • factor, runt domain, alpha subunit 2
  • core-binding factor runt domain alpha subunit 2 (acute myeloid leukemia 1 oncogene)
  • runt related transcription factor 1
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