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SARM1 Produkte

(Sterile alpha and TIR Motif Containing 1 (SARM1))

Kategorien

Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88- dependent pathway or non-TLR signaling. Negative regulator of NF- kappa-B and IRF activation (By similarity).

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Ausgewählte SARM1 Kategorien

SARM1 Antikörper

High quality antibodies with extensive validation data.

SARM1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SARM1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IF (p), IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN1387556
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p), IF, ICC, IHC
Validierungen
  • (2)
Kat. Nr. ABIN213875
Menge 0.05 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation IP, IHC (p), IHC
Validierungen
  • (2)
Kat. Nr. ABIN461750
Menge 50 μg
Datenblatt Datenblatt

Empfohlene SARM1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6207518
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SARM1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2731405
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SARM1 Produkten

Rodet, Tasiemski, Boidin-Wichlacz, Van Camp, Vuillaume, Slomianny, Salzet: "Hm-MyD88 and Hm-SARM: two key regulators of the neuroimmune system and neural repair in the medicinal leech." in: Scientific reports, Vol. 5, pp. 9624, (2015) (PubMed).

Chintala, Putris, Geno: "Activation of TLR3 promotes the degeneration of retinal ganglion cells by upregulating the protein levels of JNK3." in: Investigative ophthalmology & visual science, Vol. 56, Issue 1, pp. 505-14, (2015) (PubMed).

Murata, Sakaguchi, Kataoka, Huh: "SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria." in: Molecular biology of the cell, Vol. 24, Issue 18, pp. 2772-84, (2013) (PubMed).

Massoll, Mando, Chintala: "Excitotoxicity upregulates SARM1 protein expression and promotes Wallerian-like degeneration of retinal ganglion cells and their axons." in: Investigative ophthalmology & visual science, Vol. 54, Issue 4, pp. 2771-80, (2013) (PubMed).

Li, Moore, Vasilieva, Sui, Wong, Berne, Somasundaran, Sullivan, Luzuriaga, Greenough, Choe, Farzan: "Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus." in: Nature, Vol. 426, Issue 6965, pp. 450-4, (2003) (PubMed).

ONeill, Fitzgerald, Bowie: "The Toll-IL-1 receptor adaptor family grows to five members." in: Trends in immunology, Vol. 24, Issue 6, pp. 286-90, (2003) (PubMed).

Takeda, Kaisho, Akira: "Toll-like receptors." in: Annual review of immunology, Vol. 21, pp. 335-76, (2003) (PubMed).

Janeway, Medzhitov: "Innate immune recognition." in: Annual review of immunology, Vol. 20, pp. 197-216, (2002) (PubMed).

Synonyme und alternative Namen zu SARM1

sterile alpha and TIR motif containing 1 (SARM1), sterile alpha and HEAT/Armadillo motif containing 1 (Sarm1), sterile alpha and TIR motif containing 1 (Sarm1), sterile alpha and TIR motif containing 1 (sarm1), A830091I15Rik, C78606, MyD88-5, MyD885, SAMD2, Sarm, SARM

Bezeichner auf Proteinebene für SARM1

  • sterile alpha and TIR motif-containing protein 1
  • sterile alpha and TIR motif containing 1
  • Tir-1 homolog
  • SAM domain-containing protein 2
  • sterile alpha and Armadillo repeat protein
  • sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila
  • sterile alpha motif domain-containing protein 2
  • tir-1 homolog
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