SCN1B Produkte
(Sodium Channel, Voltage-Gated, Type I, beta (SCN1B))
Kategorien
Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
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Ausgewählte SCN1B Kategorien
SCN1B Antikörper
High quality antibodies with extensive validation data.
SCN1B Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SCN1B Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, FACS, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN654602
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7169933
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, FACS, IHC (p), EIA
Validierungen
- (3)
Kat. Nr.
ABIN954692
Menge
0.4 mL
Datenblatt
Datenblatt
Empfohlene SCN1B Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1319273
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SCN1B Produkten
: "Antisense-mediated post-transcriptional silencing of SCN1B gene modulates sodium channel functional expression." in: Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 106, Issue 1, pp. 13-29, (2014) (PubMed).: "Identification of an intra-molecular disulfide bond in the sodium channel ?1-subunit." in: Biochemical and biophysical research communications, Vol. 420, Issue 2, pp. 364-7, (2012) (PubMed).
: "Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, Issue 16, pp. 4030-42, (2004) (PubMed).
Synonyme und alternative Namen zu SCN1B
sodium channel, voltage-gated, type I, beta (Scn1b), sodium voltage-gated channel beta subunit 1 (Scn1b), sodium voltage-gated channel beta subunit 1 (SCN1B), GEFSP1Bezeichner auf Proteinebene für SCN1B
- sodium channel subunit beta-1
- sodium channel, voltage-gated, type I, beta polypeptide
- sodium channel voltage-gated type 1 beta polypeptide
- sodium channel voltage-gated type I beta polypeptide
- sodium channel, voltage-gated, type 1, beta polypeptide
- sodium channel beta-1 subunit
- sodium channel beta 1-subunit
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