SCN2A Produkte
(Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A))
Kategorien
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].
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Ausgewählte SCN2A Kategorien
SCN2A Antikörper
High quality antibodies with extensive validation data.
SCN2A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SCN2A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, ELISA, WB
Validierungen
- (2)
Kat. Nr.
ABIN6263502
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, WB, IF, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7043641
Menge
25 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB
Validierungen
- (1)
Kat. Nr.
ABIN520021
Menge
50 μL
Datenblatt
Datenblatt
Empfohlene SCN2A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1319275
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SCN2A Produkten
: "'Neonatal' Nav1.2 reduces neuronal excitability and affects seizure susceptibility and behaviour." in: Human molecular genetics, Vol. 24, Issue 5, pp. 1457-68, (2015) (PubMed).: "Quantitative proteomics reveals protein-protein interactions with fibroblast growth factor 12 as a component of the voltage-gated sodium channel 1.2 (nav1.2) macromolecular complex in Mammalian brain." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 5, pp. 1288-300, (2015) (PubMed).
: "Myelin loss and axonal ion channel adaptations associated with gray matter neuronal hyperexcitability." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 18, pp. 7272-86, (2015) (PubMed).
: "Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain." in: The Journal of comparative neurology, Vol. 523, Issue 5, pp. 814-30, (2015) (PubMed).
: "The Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening." in: PLoS ONE, Vol. 10, Issue 6, pp. e0128578, (2015) (PubMed).
: "KCNE2 modulates cardiac L-type Ca(2+) channel." in: Journal of molecular and cellular cardiology, Vol. 72, pp. 208-18, (2014) (PubMed).
: "Reciprocal changes in phosphorylation and methylation of mammalian brain sodium channels in response to seizures." in: The Journal of biological chemistry, Vol. 289, Issue 22, pp. 15363-73, (2014) (PubMed).
: "Thorough GABAergic innervation of the entire axon initial segment revealed by an optogenetic 'laserspritzer'." in: The Journal of physiology, Vol. 592, Issue Pt 19, pp. 4257-76, (2014) (PubMed).
: "Action potential initiation in neocortical inhibitory interneurons." in: PLoS biology, Vol. 12, Issue 9, pp. e1001944, (2014) (PubMed).
: "Molecular identity of axonal sodium channels in human cortical pyramidal cells." in: Frontiers in cellular neuroscience, Vol. 8, pp. 297, (2014) (PubMed).
Synonyme und alternative Namen zu SCN2A
sodium voltage-gated channel alpha subunit 2 (SCN2A), sodium channel protein type 2 subunit alpha (LOC100217927), sodium channel protein type 2 subunit alpha (LOC100389294), sodium channel protein type 2 subunit alpha (LOC100484218), sodium channel, voltage-gated, type II, alpha (Scn2a), sodium voltage-gated channel alpha subunit 2 (Scn2a), sodium channel protein type 2 subunit alpha (LOC478773), sodium channel, voltage-gated, type II, alpha subunit (SCN2A), 6430408L10, A230052E19Rik, BFIC3, BFIS3, BFNIS, EIEE11, HBA, HBSCI, HBSCII, Na(v)1.2, NAC2, NachII, Nav1.2, RII/RIIA, RNSCPIIR, SCN, Scn2a, SCN2A, SCN2A1, SCN2A2, Scn2a2, ScpIIBezeichner auf Proteinebene für SCN2A
- sodium channel, voltage-gated, type II, alpha subunit
- sodium channel protein type 2 subunit alpha-like
- sodium channel, voltage-gated, type II, alpha polypeptide 1
- RIIA sodium channel protein
- alternative product
- sodium channel protein brain II subunit alpha
- sodium channel protein type 2 subunit alpha
- sodium channel protein type II subunit alpha
- sodium channel protein, brain II subunit alpha
- sodium channel voltage-gated type II alpha polypeptide
- sodium channel, voltage-gated, type 2, alpha 1 polypeptide
- sodium channel, voltage-gated, type 2, alpha 1 subunit
- voltage-gated sodium channel subunit alpha Nav1.2
- HBSC II
- sodium channel protein, brain type 2 alpha subunit
- sodium channel, voltage-gated, type II, alpha 1 polypeptide
- sodium channel, voltage-gated, type II, alpha 2 polypeptide
- voltage-gated sodium channel subtype II
- voltage-gated sodium channel II
- sodium channel protein
- sodium channel, type II, alpha polypeptide
- sodium channel, voltage-gated, type II, alpha 1
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