SCN5A Produkte
(Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))
Kategorien
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Ausgewählte SCN5A Kategorien
SCN5A Antikörper
High quality antibodies with extensive validation data.
SCN5A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SCN5A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (6)
Kat. Nr.
ABIN185467
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Applikation
WB, IHC
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN2776088
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7182719
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene SCN5A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6220157
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SCN5A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1319281
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SCN5A Produkten
: "Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami." in: Scientific reports, Vol. 6, pp. 29538, (2016) (PubMed).: "Nicorandil improves electrical remodelling, leading to the prevention of electrically induced ventricular tachyarrhythmia in a mouse model of desmin-related cardiomyopathy." in: Clinical and experimental pharmacology & physiology, Vol. 41, Issue 1, pp. 89-97, (2013) (PubMed).
: "Similar arrhythmicity in hypertrophic and fibrotic cardiac cultures caused by distinct substrate-specific mechanisms." in: Cardiovascular research, Vol. 97, Issue 1, pp. 171-81, (2012) (PubMed).
: "Optical mapping of cryoinjured rat myocardium grafted with mesenchymal stem cells." in: American journal of physiology. Heart and circulatory physiology, Vol. 302, Issue 1, pp. H270-7, (2011) (PubMed).
: "The histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces cardiac arrhythmias in dystrophic mice." in: Cardiovascular research, Vol. 87, Issue 1, pp. 73-82, (2010) (PubMed).
: "Voltage-gated Na+ channel SCN5A is a key regulator of a gene transcriptional network that controls colon cancer invasion." in: Cancer research, Vol. 70, Issue 17, pp. 6957-67, (2010) (PubMed).
: "Sodium channel mutations and susceptibility to heart failure and atrial fibrillation." in: JAMA, Vol. 293, Issue 4, pp. 447-54, (2005) (PubMed).
Synonyme und alternative Namen zu SCN5A
sodium voltage-gated channel alpha subunit 5 (SCN5A), sodium channel, voltage-gated, type V, alpha (Scn5a), sodium voltage-gated channel alpha subunit 5 (Scn5a), CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, mH1, Nav1.5, Nav1.5c, PFHB1, SCAL, SkM1, SkM2, SSS1, VF1Bezeichner auf Proteinebene für SCN5A
- sodium channel, voltage-gated, type V, alpha subunit
- voltage-gated sodium channel type V alpha
- sodium channel protein type 5 subunit alpha
- voltage-gated sodium channel cardiac isoform Nav1.5
- sodium channel protein cardiac muscle subunit alpha
- sodium channel protein type V subunit alpha
- sodium channel voltage-gated type V alpha polypeptide
- sodium channel, voltage-gated, type V, alpha polypeptide
- voltage-gated sodium channel subunit alpha Nav1.5
- cardiac tetrodotoxin-insensitive voltage-dependent sodium channel alpha subunit
- cardiac sodium channel
- sodium channel alpha subunit
- sodium channel, voltage-gated, type V, alpha (long QT syndrome 3)
- voltage-gated sodium channel alpha subunit
- sodium channel, voltage-gated, type V, alpha polypeptide (long (electrocardiographic) QT syndrome 3)
- sodium channel, voltage-gated, type 5, alpha subunit
- voltage-gated sodium channel Nav1.5c
- oltage-gated sodium channel type V alpha
- voltage-dependent sodium channel SCN10A
- voltage-gated sodium channel H
- voltage-gated sodium channel type V alpha polypeptide
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