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SCN7A Produkte

(Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A))

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This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics\; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels\; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011].

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Ausgewählte SCN7A Kategorien

SCN7A Antikörper

High quality antibodies with extensive validation data.

Empfohlene SCN7A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, WB, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7169925
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IF
Validierungen
  • (1)
Kat. Nr. ABIN7184122
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Rat
Applikation ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p)
Validierungen
  • (1)
Kat. Nr. ABIN1386696
Menge 100 μL
Datenblatt Datenblatt

Neueste Publikationen zu unseren SCN7A Produkten

Gorter, Zurolo, Iyer, Fluiter, van Vliet, Baayen, Aronica: "Induction of sodium channel Na(x) (SCN7A) expression in rat and human hippocampus in temporal lobe epilepsy." in: Epilepsia, Vol. 51, Issue 9, pp. 1791-800, (2010) (PubMed).

Synonyme und alternative Namen zu SCN7A

sodium channel, voltage-gated, type VII, alpha (Scn7a), sodium voltage-gated channel alpha subunit 7 (Scn7a), sodium voltage-gated channel alpha subunit 7 (SCN7A), 1110034K09Rik, AI642000, Na-G, NaG, Nav2, Nav2.1, Nav2.2, Nav2.3, Nax, Scn6a, SCN6A

Bezeichner auf Proteinebene für SCN7A

  • sodium channel, voltage-gated, type VI, alpha polypeptide
  • sodium channel, voltage-gated, type VII, alpha polypeptide
  • sodium channel protein type 7 subunit alpha
  • sodium channel voltage-gated type VI alpha polypeptide
  • sodium channel, voltage-gated, type 6, alpha polypeptide
  • putative voltage-gated sodium channel subunit alpha Nax
  • sodium channel protein cardiac and skeletal muscle subunit alpha
  • sodium channel protein type VII subunit alpha
  • voltage-dependent sodium channel alpha subunit
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