SCN8A Produkte
(Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))
Kategorien
This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010].
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Ausgewählte SCN8A Kategorien
SCN8A Antikörper
High quality antibodies with extensive validation data.
SCN8A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SCN8A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN520023
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
WB, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7075647
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Applikation
WB, IHC
Validierungen
- (4)
Kat. Nr.
ABIN2776200
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene SCN8A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1319283
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SCN8A Produkten
: "Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain." in: The Journal of comparative neurology, Vol. 523, Issue 5, pp. 814-30, (2015) (PubMed).: "Axon initial segment-associated microglia." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 5, pp. 2283-92, (2015) (PubMed).
: "BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 18, pp. 7082-94, (2015) (PubMed).
: "The Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening." in: PLoS ONE, Vol. 10, Issue 6, pp. e0128578, (2015) (PubMed).
: "A unique ion channel clustering domain on the axon initial segment of mammalian neurons." in: The Journal of comparative neurology, Vol. 522, Issue 11, pp. 2594-608, (2014) (PubMed).
: "Glial ankyrins facilitate paranodal axoglial junction assembly." in: Nature neuroscience, Vol. 17, Issue 12, pp. 1673-81, (2014) (PubMed).
: "Blast wave exposure impairs memory and decreases axon initial segment length." in: Journal of neurotrauma, Vol. 30, Issue 9, pp. 741-51, (2013) (PubMed).
: "Aberrant sodium channel activity in the complex seizure disorder of Celf4 mutant mice." in: The Journal of physiology, Vol. 591, Issue Pt 1, pp. 241-55, (2013) (PubMed).
: "Effects of adult neural precursor-derived myelination on axonal function in the perinatal congenitally dysmyelinated brain: optimizing time of intervention, developing accurate prediction models, and ..." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 29, pp. 11899-915, (2013) (PubMed).
: "FGF14 localization and organization of the axon initial segment." in: Molecular and cellular neurosciences, Vol. 56, pp. 393-403, (2013) (PubMed).
Synonyme und alternative Namen zu SCN8A
sodium voltage-gated channel alpha subunit 8 (SCN8A), sodium voltage-gated channel alpha subunit 8 (Scn8a), sodium channel, voltage-gated, type VIII, alpha (Scn8a), AI853486, C630029C19Rik, CERIII, CIAT, dmu, EIEE13, MED, med, mnd-2, mnd2, NaCh6, Nav1.6, nmf2, nmf58, nmf335, nur14, PN4, sealBezeichner auf Proteinebene für SCN8A
- hNa6/Scn8a voltage-gated sodium channel
- sodium channel protein type 8 subunit alpha
- voltage-gated sodium channel subunit alpha Nav1.6
- Na+ channel
- PN4
- naCh6
- peripheral nerve protein type 4
- sodium channel 6
- sodium channel protein type VIII subunit alpha
- sodium channel voltage-gated type VIII alpha polypeptide
- sodium channel, voltage-gated, type 8, alpha polypeptide
- sodium channel, voltage-gated, type 8, alpha subunit
- sodium channel, voltage-gated, type VIII, alpha polypeptide
- ataxia 3
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