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SCNN1A Produkte

(Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009].

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Ausgewählte SCNN1A Kategorien

SCNN1A Antikörper

High quality antibodies with extensive validation data.

SCNN1A ELISA Kits

Reliable ELISA kits for a wide range of species.

SCNN1A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SCNN1A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Applikation WB, IHC, IF, IP, ICC
Validierungen
  • (19)
  • (5)
Kat. Nr. ABIN863203
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Rat
Applikation WB, IHC, IF, ICC
Validierungen
  • (19)
  • (5)
Kat. Nr. ABIN863204
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Rat
Applikation WB, IHC, IF, IP, ICC
Validierungen
  • (19)
  • (4)
Kat. Nr. ABIN863202
Menge 100 μg
Datenblatt Datenblatt

Empfohlene SCNN1A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959542
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959543
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5651663
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SCNN1A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7407787
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7397414
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7417705
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SCNN1A Produkten

Sudarikova, Bychkov, Kulbatskii, Chubinskiy-Nadezhdin, Shlepova, Shulepko, Koshelev, Kirpichnikov, Lyukmanova: "Mambalgin-2 Inhibits Lung Adenocarcinoma Growth and Migration by Selective Interaction With ASIC1/α-ENaC/γ-ENaC Heterotrimer." in: Frontiers in oncology, Vol. 12, pp. 904742, (2022) (PubMed).

Bychkov, Kirichenko, Shulepko, Mikhaylova, Kirpichnikov, Lyukmanova: "Mambalgin-2 Inhibits Growth, Migration, and Invasion of Metastatic Melanoma Cells by Targeting the Channels Containing an ASIC1a Subunit Whose Up-Regulation Correlates with Poor Survival Prognosis." in: Biomedicines, Vol. 9, Issue 10, (2021) (PubMed).

Khedr, Palygin, Pavlov, Blass, Levchenko, Alsheikh, Brands, El-Meanawy, Staruschenko: "Increased ENaC activity during kidney preservation in Wisconsin solution." in: BMC nephrology, Vol. 20, Issue 1, pp. 145, (2020) (PubMed).

Scortegagna, Berthon, Settas, Giannakou, Garcia, Li, James, Liddington, Vilches-Moure, Stratakis, Ronai: "The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion." in: JCI insight, Vol. 2, Issue 23, (2019) (PubMed).

Blass, Klemens, Brands, Palygin, Staruschenko: "Postprandial Effects on ENaC-Mediated Sodium Absorption." in: Scientific reports, Vol. 9, Issue 1, pp. 4296, (2019) (PubMed).

Li, Chen, Yang, He, He, Xia, Zhang, Xiang: "Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3." in: International journal of oncology, Vol. 53, Issue 3, pp. 1129-1137, (2018) (PubMed).

Liang, Wang, Yang, Niu, Hu, Zhang, Wu, Yu, Chen, Song, Zhang, Ma: "Oxidized low-density lipoprotein stimulates epithelial sodium channels in endothelial cells of mouse thoracic aorta." in: British journal of pharmacology, Vol. 175, Issue 8, pp. 1318-1328, (2018) (PubMed).

Czikora, Alli, Sridhar, Matthay, Pillich, Hudel, Berisha, Gorshkov, Romero, Gonzales, Wu, Huo, Su, Verin, Fulton, Chakraborty, Eaton, Lucas: "Epithelial Sodium Channel-α Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction." in: Frontiers in immunology, Vol. 8, pp. 842, (2017) (PubMed).

Pavlov, Levchenko, Ilatovskaya, Moreno, Staruschenko: "Renal sodium transport in renin-deficient Dahl salt-sensitive rats." in: Journal of the renin-angiotensin-aldosterone system : JRAAS, Vol. 17, Issue 3, (2017) (PubMed).

Yamamoto, Hotta, Maeda, Kataoka, Maeda, Hamakawa, Sasaki, Yasui, Asai, Kimura: "Mineralocorticoid receptor stimulation induces urinary storage dysfunction via upregulation of epithelial sodium channel expression in the rat urinary bladder epithelium." in: Journal of pharmacological sciences, Vol. 130, Issue 4, pp. 219-25, (2016) (PubMed).

Synonyme und alternative Namen zu SCNN1A

sodium channel epithelial 1 alpha subunit (Scnn1a), sodium channel epithelial 1 alpha subunit (SCNN1A), sodium channel, nonvoltage-gated 1 alpha (Scnn1a), sodium channel, non voltage gated 1 alpha subunit L homeolog (scnn1a.L), alphaxENaC, BESC2, besc2, ENaC, ENAC, ENaCa, enaca, ENaCalpha, mENaC, SCNEA, SCNN1, Scnn1, scnn1, SCNN1A

Bezeichner auf Proteinebene für SCNN1A

  • SCNEA
  • alpha-ENaC
  • alpha-NaCH
  • amiloride-sensitive sodium channel subunit alpha
  • epithelial Na(+) channel subunit alpha
  • epithelial sodium channel alpha subunit
  • nonvoltage-gated sodium channel 1 subunit alpha
  • sodium channel, nonvoltage-gated, type I, alpha
  • alpha ENaC-2
  • amiloride-sensitive epithelial sodium channel alpha subunit
  • amiloride-sensitive sodium channel subunit alpha 2
  • nasal epithelial sodium channel alpha subunit
  • sodium channel, nonvoltage-gated 1 alpha
  • ENaC alpha
  • amiloride-sensitive epithelial sodium channel
  • sodium channel, nonvoltage-gated, type I, alpha polypeptide
  • alpha ENaC
  • epithelial sodium channel ENaC alpha subunit
  • alpha cENaC 431
  • amiloride-sensitve epithelial sodium channel alpha subunit
  • alpha-subunit renal epithelial sodium channel
  • epithelium sodium channel alpha subunit
  • sodium channel, nonvoltage-gated 1, alpha
  • amiloride-sensitive sodium channel alpha subunit
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